AI-2-mediated signalling in bacteria

CS Pereira, JA Thompson… - FEMS microbiology …, 2013 - academic.oup.com
Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

Biomolecular Mechanisms of Pseudomonas aeruginosa and Escherichia coli Biofilm Formation

G Laverty, SP Gorman, BF Gilmore - Pathogens, 2014 - mdpi.com
Pseudomonas aeruginosa and Escherichia coli are the most prevalent Gram-negative
biofilm forming medical device associated pathogens, particularly with respect to catheter …

Chemical challenges to bacterial AHL signaling in the environment

AW Decho, RL Frey, JL Ferry - Chemical reviews, 2011 - ACS Publications
Since the seminal observation that bacterial cells produce intracellular molecules that trigger
bioluminescence, 1 a great deal has been learned regarding the process now termed …

LsrF, a coenzyme A-dependent thiolase, catalyzes the terminal step in processing the quorum sensing signal autoinducer-2

JC Marques, IK Oh, DC Ly, P Lamosa… - Proceedings of the …, 2014 - National Acad Sciences
The quorum sensing signal autoinducer-2 (AI-2) regulates important bacterial behaviors,
including biofilm formation and the production of virulence factors. Some bacteria, such as …

The ancestral stringent response potentiator, DksA has been adapted throughout Salmonella evolution to orchestrate the expression of metabolic, motility, and …

H Cohen, B Adani, E Cohen, B Piscon, S Azriel… - Gut …, 2022 - Taylor & Francis
DksA is a conserved RNA polymerase-binding protein known to play a key role in the
stringent response of proteobacteria species, including many gastrointestinal pathogens …

The organophosphate malathion disturbs gut microbiome development and the quorum-Sensing system

B Gao, L Chi, P Tu, X Bian, J Thomas, H Ru, K Lu - Toxicology Letters, 2018 - Elsevier
The gut microbiome has tremendous potential to impact health and disease. Various
environmental toxicants, including insecticides, have been shown to alter gut microbiome …

Cell-to-Cell Signaling in Escherichia coli and Salmonella

MM Kendall, V Sperandio - EcoSal Plus, 2014 - Am Soc Microbiol
Bacteria must be able to respond rapidly to changes in the environment to survive. One
means of coordinating gene expression relies on tightly regulated and complex signaling …

Crystal structures of the LsrR proteins complexed with phospho-AI-2 and two signal-interrupting analogues reveal distinct mechanisms for ligand recognition

JH Ha, Y Eo, A Grishaev, M Guo, JAI Smith… - Journal of the …, 2013 - ACS Publications
Quorum sensing (QS) is a cell-to-cell communication system responsible for a variety of
bacterial phenotypes including virulence and biofilm formation. QS is mediated by small …

Chemo-enzymatic synthesis of the carbohydrate antigen N-glycolylneuraminic acid from glucose

OMT Pearce, A Varki - Carbohydrate research, 2010 - Elsevier
N-Glycolylneuraminic acid (Neu5Gc) is a non-human sialic acid, which may play a
significant role in human pathologies, such as cancer and vascular disease. Further studies …

Metabolic activities of marine ammonia‐oxidizing archaea orchestrated by quorum sensing

O Pereira, W Qin, PE Galand, D Debroas, R Lami… - Mlife, 2024 - Wiley Online Library
Ammonia‐oxidizing archaea (AOA) play crucial roles in marine carbon and nitrogen cycles
by fixing inorganic carbon and performing the initial step of nitrification. Evaluation of carbon …