Dyneins make up a family of AAA+ motors that move toward the minus end of microtubules.
Cytoplasmic dynein is responsible for transporting intracellular cargos in interphase cells …

Echoing the repeated convergent evolution of flight and vision in large eukaryotes,
propulsive swimming motility has evolved independently in microbes in each of the three …

Photosynthetic organisms like plants and algae can use sunlight to produce lipids as
important metabolic compounds. Plant-derived triacylglycerols (TAGs) are valuable for …

Primary ciliary dyskinesia (PCD) is a recessively inherited disease that leads to chronic
respiratory disorders owing to impaired mucociliary clearance. Conventional transmission …

Axonemal dynein motors drive ciliary motility and can consist of up to twenty distinct
components with a combined mass of~ 2 MDa. In mammals, failure of dyneins to assemble …

This review outlines the current knowledge of the functional diversity of axonemal dyneins,
as revealed by studies with the model organism Chlamydomonas. Axonemal dyneins, which …

Microtubule diversity, arising from the utilization of different tubulin genes and from
posttranslational modifications, regulates many cellular processes including cell division …

The axoneme—the conserved core of eukaryotic cilia and flagella—contains highly
specialized doublet microtubules (DMTs). A long-standing question is what protein (s) …

Outer and inner dynein arms generate force for the flagellar/ciliary bending motion. Although
nucleotide-induced structural change of dynein heavy chains (the ATP-driven motor) was …

Motility of cilia/flagella is generated by a coordinated activity of thousands of dyneins. Inner
dynein arms (IDAs) are particularly important for the formation of ciliary/flagellar waveforms …