Oxyresveratrol: Sources, productions, biological activities, pharmacokinetics, and delivery systems

K Likhitwitayawuid - Molecules, 2021 - mdpi.com
Oxyresveratrol has recently attracted much research attention due to its simple chemical
structure and diverse therapeutic potentials. Previous reviews describe the chemistry and …

Resveratrol and its role in the management of B-cell malignancies—A recent update

DS Gupta, V Gadi, G Kaur, M Chintamaneni, HS Tuli… - Biomedicines, 2023 - mdpi.com
The growing incidence of B cell malignancies globally has prompted research on the
pharmacological properties of phytoconstituents in cancer management. Resveratrol, a …

Principal Component Analysis (PCA) of Molecular Descriptors for Improving Permeation through the Blood–Brain Barrier of Quercetin Analogues

N Pavlović, N Milošević Sopta, D Mitrović… - International Journal of …, 2023 - mdpi.com
Despite its beneficial pharmacological effects in the brain, partly by modulating inositol
phosphate multikinase (IPMK) activity, the therapeutic use of quercetin is limited due to its …

Exploring the molecular interactions and binding affinity of resveratrol and calcitriol with RAGE and its intracellular proteins and kinases involved in colorectal cancer

YS Muthyalaiah, S Arockiasamy… - Journal of Biomolecular …, 2024 - Taylor & Francis
Colorectal cancer (CRC) burden is progressively increasing in young population due to
dietary and lifestyle pattern. Advanced glycation end products (AGEs), one of the dietary …

Piceatannol selectively inhibited the JNK3 enzyme and augmented apoptosis through inhibition of Bcl‐2/Cyt‐c/caspase‐dependent pathways in the oxygen–glucose …

RK Rajan, M Ramanathan - Chemical Biology & Drug Design, 2024 - Wiley Online Library
JNK3, a neuronal kinase activated by stress, plays a role in stress‐induced apoptosis,
leading to neuronal cell death following cerebral ischemia. This study investigates the …

Antimetastatic potential of quercetin analogues with improved pharmacokinetic profile: a pharmacoinformatic preliminary study

N Pavlović, N Milošević, M Đjanić… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Background: Urokinase-type plasminogen activator (uPA) system is a crucial pathway for
tumor invasion and metastasis. Recently, multiple anticancer effects of quercetin have been …

Activation of Sarco/Endoplasmic Reticulum Ca2+-ATPase by Natural Polyphenolic Compounds. Mechanism of Protection against Oxidative Stress

V Heger, B Barbora, M Majekova, P Rezbarikova… - 2023 - preprints.org
Many redox diseases, including diabetes, are associated with an imbalance of calcium
homeostasis, regulated mainly by a Ca2+-ATPase pump (SERCA). Dysfunction of this …

Insilico Insights into Resveratrol as a Potential Inhibitor of Mycobacterium Tuberculosis Enoyl-ACP Reductase (InhA) Protein: Insilico Insights into Mycobacterium …

O Ullah, N Hanif, AQ Mufti, F Amjad… - Futuristic …, 2024 - fbtjournal.com
Mycobacterium tuberculosis, the causative agent of tuberculosis, is a global cause of death.
Thus, the development of innovative treatment strategies is required. Objective: To develop …

Construction of lightweight big data experimental platform based on dockers container

Y Ren - International Journal of Information System Modeling …, 2020 - igi-global.com
To reduce the large data experiment platform construction cost and reduce the learning
difficulty big data, this article is based on virtualization technology through the Docker …