It became apparent several years ago that RNAseq and exome files prepared from tissue
could be mined for adaptive immune receptor (IR) recombinations, which has given extra …

The evaluation of physicochemical characteristics of extensive adaptive immune receptor
(IR) recombination sequence collections has led to the discovery of many correlations of …

Introduction: One of the most pressing goals for cancer immunotherapy at this time is the
identification of actionable antigens. Methods: This study relies on the following …

Ovarian cancer continues to present significant challenges for early detection and treatment,
indicating a need for novel approaches to improve disease outcomes. In this report, we …

Background Uterine corpus endometrial carcinoma (UCEC) is a common malignant cancer
type which affects the health of women worldwide. However, its molecular mechanism has …

In the diffuse large B-cell lymphoma (DLBCL) setting, we examined lymph node biopsy, T-
cell receptor features, and the DLBLC patient human leukocyte antigen (HLA) alleles, to …

With the advent of large collections of adaptive immune receptor recombination reads
representing cancer, there is the opportunity to further investigate the adaptive immune …

Overexpression of the secretory protein renalase-1 negatively impacts the survival of
melanoma and pancreatic cancer patients, while inhibition of renalase-1 signaling drives …

Simple Summary The chemical complementarity of glioblastoma, tumor-resident T-cell
receptors and cancer testis antigens were associated with a worse outcome. Additionally …

T-lymphocytes have been implicated in facilitating a pro-inflammatory, pro-tumorigenic
microenvironment that worsens prognosis for esophageal carcinoma (ESCA). In this study …