Neurodevelopmental disorders

A Thapar, M Cooper, M Rutter - The Lancet Psychiatry, 2017 - thelancet.com
Neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD) and
autism spectrum disorder, although most commonly considered in childhood, can be lifelong …

Machine learning in attention-deficit/hyperactivity disorder: new approaches toward understanding the neural mechanisms

M Cao, E Martin, X Li - Translational Psychiatry, 2023 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent and heterogeneous
neurodevelopmental disorder in children and has a high chance of persisting in adulthood …

What is an emotional disorder? A transdiagnostic mechanistic definition with implications for assessment, treatment, and prevention.

JR Bullis, H Boettcher, S Sauer‐Zavala… - … : Science and practice, 2019 - psycnet.apa.org
We present a transdiagnostic definition of the commonly used, but poorly defined, term
emotional disorder. This definition transcends and possibly complements traditional …

Evaluation of the persistence, remission, and emergence of attention-deficit/hyperactivity disorder in young adulthood

JC Agnew-Blais, GV Polanczyk, A Danese… - JAMA …, 2016 - jamanetwork.com
Importance Attention-deficit/hyperactivity disorder (ADHD) is now recognized to occur in
adulthood and is associated with a range of negative outcomes. However, less is known …

The p factor: genetic analyses support a general dimension of psychopathology in childhood and adolescence

AG Allegrini, R Cheesman, K Rimfeld… - Journal of child …, 2020 - Wiley Online Library
Background Diverse behaviour problems in childhood correlate phenotypically, suggesting
a general dimension of psychopathology that has been called the p factor. The shared …

ADHD diagnosis and treatment guidelines: a historical perspective

ML Wolraich, E Chan, T Froehlich, RL Lynch… - …, 2019 - publications.aap.org
Attention-deficit/hyperactivity disorder (ADHD) is the most common behavioral condition and
the second most common chronic illness in children. The observance of specific behaviors …

Genetic and environmental risk factors associated with trajectories of depression symptoms from adolescence to young adulthood

ASF Kwong, JA López-López, G Hammerton… - JAMA Network …, 2019 - jamanetwork.com
Importance Less favorable trajectories of depressive mood from adolescence to early
adulthood are associated with current and later psychopathology, impaired educational …

Life span studies of ADHD—conceptual challenges and predictors of persistence and outcome

A Caye, J Swanson, A Thapar, M Sibley… - Current psychiatry …, 2016 - Springer
There is a renewed interest in better conceptualizing trajectories of attention-
deficit/hyperactivity disorder (ADHD) from childhood to adulthood, driven by an increased …

The importance of a developmental perspective in Psychiatry: what do recent genetic-epidemiological findings show?

A Thapar, L Riglin - Molecular psychiatry, 2020 - nature.com
There is growing appreciation that a developmental perspective is helpful in Psychiatry.
However, clinical practice and research, especially in an era of very large sample sizes …

Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder

VM Rajagopal, J Duan, L Vilar-Ribó, J Grove… - Nature …, 2022 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder with onset
in childhood (childhood ADHD); two-thirds of affected individuals continue to have ADHD in …