The angiotensin I converting enzyme has two important functions: it inactivates bradykinin
and converts angiotensin I to angiotensin II. Inhibition of the enzyme blocks the renin …

There have been considerable advances in understanding the metabolic role of the
endothelial lining cells of the blood vessels. Angiotensin-converting enzyme activity is …

Fluorescein-labeled antibody to rabbit pulmonary angiotensin-converting enzyme localized
in the vascular endothelium of rabbit lung, liver, adrenal cortex, pancreas, kidney, and …

• Interest in particular biologically active substances waxes and wanes. Investigators rush
into a newly opened field, solve a few problems, and frequently raise more; then they rush …

In 1976 I wrote a monograph on lysosomes (Lysosomes: A Survey, Springer Verlag, Vienna)
that was intended as an up-to-date, comprehensive survey. Whatever success I may have …

The renin-angiotensin system has an important role in maintaining elevated blood pressure
levels in certain forms of experimental and human hypertension. Renin, an enzyme …

Angiotensin-converting enzyme has been solubilized from a particulate fraction of rabbit
lung and purified to apparent homogeneity in 11% yield by a procedure including …

Since publication of the previous edition of this Handbook in 1970, much new information
has been gathered about kininases, the enzymes that inactivate kinins. This chapter …

This article reviews the discovery and biochemical properties of angiotensin-converting
enzyme inhibitors, specifically the research at the Merck Sharp and Dohme Research …

Rabbit testicular dipeptidyl carboxypeptidase activity was purified by a procedure exploiting
its affinity for N-alpha-[1-(S)-carboxy-3-phenylpropyl]-L-lysyl-L-proline. The molecular …