Key Proteins of Replication Stress Response and Cell Cycle Control as Cancer Therapy Targets
AI Khamidullina, YE Abramenko, AV Bruter… - International Journal of …, 2024 - mdpi.com
Replication stress (RS) is a characteristic state of cancer cells as they tend to exchange
precision of replication for fast proliferation and increased genomic instability. To overcome …
precision of replication for fast proliferation and increased genomic instability. To overcome …
First-in-Human study of the ataxia telangiectasia and rad3-related (ATR) inhibitor tuvusertib (M1774) as monotherapy in patients with solid tumors
TA Yap, AW Tolcher, R Plummer, JK Mukker… - Clinical Cancer …, 2024 - AACR
Abstract Purpose: Tuvusertib (M1774) is a potent, selective, orally administered ataxia
telangiectasia and Rad3-related (ATR) protein kinase inhibitor. This first-in-human study …
telangiectasia and Rad3-related (ATR) protein kinase inhibitor. This first-in-human study …
Ruthenium Drug BOLD-100 Regulates BRAFMT Colorectal Cancer Cell Apoptosis through AhR/ROS/ATR Signaling Axis Modulation
D Griffin, R Carson, D Moss, T Sessler… - Molecular Cancer …, 2024 - aacrjournals.org
Patients with class I V600E BRAF-mutant (MT) colorectal cancer exhibit a poor prognosis,
and their response to combined anti-BRAF/EGFR inhibition remains limited. An unmet need …
and their response to combined anti-BRAF/EGFR inhibition remains limited. An unmet need …
[PDF][PDF] Solusyklin normaali säätely ja sen häiriöt
J Rantala - 2024 - utupub.fi
Solusykli on erilaisten solun sisäisten ja ulkoisten säätelytekijöiden tarkasti säätelemä
prosessi. Nämä säätelijät sekä solusyklin tarkistuspisteet eri vaiheiden siirtymäkohdissa …
prosessi. Nämä säätelijät sekä solusyklin tarkistuspisteet eri vaiheiden siirtymäkohdissa …
[PDF][PDF] Pokroky v léčbě vysoce rizikových leukémií a lymfomů
EMA JOUDALOVÁ - is.muni.cz
Pokroky v léčbě vysoce rizikových leukémií a lymfomů Page 1 MASARYKOVA UNIVERZITA
PŘÍRODOVĚDECKÁ FAKULTA Pokroky v léčbě vysoce rizikových leukémií a lymfomů Bakalářská …
PŘÍRODOVĚDECKÁ FAKULTA Pokroky v léčbě vysoce rizikových leukémií a lymfomů Bakalářská …