Emerging mechanistic understanding of cilia function in cellular signalling
Primary cilia are solitary, immotile sensory organelles present on most cells in the body that
participate broadly in human health, physiology and disease. Cilia generate a unique …
participate broadly in human health, physiology and disease. Cilia generate a unique …
Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia
VR Palicharla, SH Hwang, BN Somatilaka… - Molecular biology of …, 2023 - Am Soc Cell Biol
The primary cilium is a nexus for cell signaling and relies on specific protein trafficking for
function. The tubby family protein TULP3 transports integral membrane proteins into cilia …
function. The tubby family protein TULP3 transports integral membrane proteins into cilia …
[HTML][HTML] Molecular and structural perspectives on protein trafficking to the primary cilium membrane
V Reddy Palicharla… - Biochemical Society …, 2024 - portlandpress.com
The primary cilium is a dynamic subcellular compartment templated from the mother
centriole or basal body. Cilia are solitary and tiny, but remarkably consequential in cellular …
centriole or basal body. Cilia are solitary and tiny, but remarkably consequential in cellular …
NRXN3 mutations cause developmental delay, movement disorder, and behavioral problems: CRISPR edited cells based WES results
NRXN3 gene encodes neurexin-III which is a Neural Cell Adhesion Molecule (NCAM) with
important synaptic functions in the brain. Neurexin-III deficiency could affect synapse …
important synaptic functions in the brain. Neurexin-III deficiency could affect synapse …
[HTML][HTML] A Highlights from MBoC Selection: Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia
VR Palicharla, SH Hwang, BN Somatilaka… - Molecular Biology of …, 2023 - ncbi.nlm.nih.gov
The primary cilium is a nexus for cell signaling and relies on specific protein trafficking for
function. The tubby family protein TULP3 transports integral membrane proteins into cilia …
function. The tubby family protein TULP3 transports integral membrane proteins into cilia …
Exome data reanalysis solved case in undetermined nephropathy with detection of TULP3-truncating variant
T Robert, B Savenkoff, T Legris… - Nephrology Dialysis …, 2023 - academic.oup.com
Chronic kidney disease (CKD) is a public health problem. In a large national registry, 20%–
25% of patients with endstage kidney disease have been reported with an undetermined …
25% of patients with endstage kidney disease have been reported with an undetermined …
Novel insight into the ectodermal dysplasia 11A: Splicing variant of the EDARADD gene in a family with clinical variability and literature review
N Fazelzadeh Haghighi, N Kamal… - The Journal of …, 2023 - Wiley Online Library
Pathogenic variants in the EDARADD gene result in autosomal recessive and autosomal
dominant ectodermal dysplasia. This article reports on the fourth family in the world with …
dominant ectodermal dysplasia. This article reports on the fourth family in the world with …
A Rare Case Mimicking Congenital Hepatic Fibrosis
C Jiang, M Lian, X Ma - Gastroenterology, 2024 - Elsevier
Author Contributions: Chenyi Jiang and Min Lian designed the study with assistance from
Xiong Ma. Chenyi Jiang and Min Lian collected the data. Chenyi Jiang prepared the graphs …
Xiong Ma. Chenyi Jiang and Min Lian collected the data. Chenyi Jiang prepared the graphs …