In recent years, there have been multiple breakthroughs in cancer immunotherapy, with
immune checkpoint inhibitors becoming the most promising treatment strategy. However …

The continuous, in-depth exploration of the occurrence and development of cancer has
shown that immune cell dysfunction is closely associated with tumor progression and poor …

Background: Ferroptosis is a new type of programmed cell death which has been reported to
be involved in the development of various cancers. In this study, we attempted to explore the …

Aims: This study aimed to reveal the possible molecular mechanism of n6-methyladenosine
(m6A) methylation regulator FTO in the biological activities of ovarian cancer (OC) based on …

The discovery of CTLA-4 and PD-1 checkpoints has prompted scientific researchers and the
pharmaceutical industry to develop and conduct extensive research on tumor-specific …

Introduction The development of therapeutic antibodies targeting immune checkpoint
molecules (ICMs) that induce long-term remissions in cancer patients has revolutionized …

CD155, also known as the poliovirus receptor, is an adhesion molecule often overexpressed
in tumors of different origins where it promotes cell migration and proliferation. In addition to …

In tumor therapeutics, the transition from conventional cytotoxic drugs to targeted molecular
therapies, such as those targeting receptor tyrosine kinases, has been pivotal. Despite this …

Background Melanoma is an extremely aggressive type of skin cancer and experiencing a
expeditiously rising mortality in a current year. Exploring new potential prognostic …

To screen potential pivotal targets in sepsis through peripheral blood. Septic patients (n= 23)
and healthy volunteers (n= 10) were enrolled according to SEPSIS 3.0. Peripheral blood …