A concise review on Artemisia annua L.: A major source of diverse medicinal compounds

R Soni, G Shankar, P Mukhopadhyay… - Industrial Crops and …, 2022 - Elsevier
Malaria is one of the major global health concerns that affect millions of people worldwide
annually, especially people residing in the developing countries. The previously …

Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research

OPS Patel, RM Beteck, LJ Legoabe - European journal of medicinal …, 2021 - Elsevier
Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …

Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro/in vivo studies and live-cell imaging

L Herrmann, M Leidenberger, AS de Morais, C Mai… - Chemical …, 2023 - pubs.rsc.org
Malaria is one of our planet's most widespread and deadliest diseases, and there is an ever-
consistent need for new and improved pharmaceuticals. Natural products have been an …

Widely targeted metabolomics analysis of enriched secondary metabolites and determination of their corresponding antioxidant activities in Elaeagnus angustifolia var …

Y Wang, H Li, X Li, C Wang, Q Li, M Xu, X Guan, Z Lan… - Food Chemistry, 2022 - Elsevier
Elaeagnus angustifolia var. orientalis (L.) Kuntze fruit contains a large number of naturally
occurring molecules present as glycoside, methylated, and methyl ester conjugates, which …

The role of the iron protoporphyrins heme and hematin in the antimalarial activity of endoperoxide drugs

HC Quadros, MCB Silva, DRM Moreira - Pharmaceuticals, 2022 - mdpi.com
Plasmodium has evolved to regulate the levels and oxidative states of iron protoporphyrin IX
(Fe-PPIX). Antimalarial endoperoxides such as 1, 2, 4-trioxane artemisinin and 1, 2, 4 …

[HTML][HTML] Effects and mechanisms of Chinese herbal medicine on IgA nephropathy

S Ma, M Zhao, M Chang, X Shi, Y Shi, Y Zhang - Phytomedicine, 2023 - Elsevier
Abstract Background Immunoglobulin A nephropathy (IgAN), is the main cause of end-stage
renal disease, that causes serious physical and psychological burden to patients worldwide …

Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites

K Ashraf, S Tajeri, CS Arnold… - Life Science …, 2022 - life-science-alliance.org
Artemisinin-based combination therapies (ACT) are the frontline treatments against malaria
worldwide. Recently the use of traditional infusions from Artemisia annua (from which …

Plasmodium falciparum sexual parasites regulate infected erythrocyte permeability

G Bouyer, D Barbieri, F Dupuy, A Marteau… - Communications …, 2020 - nature.com
To ensure the transport of nutrients necessary for their survival, Plasmodium falciparum
parasites increase erythrocyte permeability to diverse solutes. These new permeation …

Characterization of antimalarial activity of artemisinin-based hybrid drugs

HC Quadros, L Herrmann, J Manaranche… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
In response to the spread of artemisinin (ART) resistance, ART-based hybrid drugs were
developed, and their activity profile was characterized against drug-sensitive and drug …

Three-Dimensional Porous PVDF Foam Imprinted Membranes with High Flux and Selectivity toward Artemisinin/Artemether

W Bian, R Zhang, X Chen, C Zhang, M Meng - Molecules, 2023 - mdpi.com
In this study, a new 3D porous PVDF-foam-imprinted membrane (PPIM) for the selective
separation of artemisinin (ART) was first prepared via the dopamine adhesion of pre …