Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring
W Li, JB Liu, LK Hou, F Yu, J Zhang, W Wu, XM Tang… - Molecular cancer, 2022 - Springer
Primary lung cancer is one of the most common malignant tumors in China. Approximately
60% of lung cancer patients have distant metastasis at the initial diagnosis, so it is …
60% of lung cancer patients have distant metastasis at the initial diagnosis, so it is …
Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma
T Liu, C Han, P Fang, Z Ma, X Wang, H Chen… - Journal of hematology & …, 2022 - Springer
Background Besides featured glucose consumption, recent studies reveal that cancer cells
might prefer “addicting” specific energy substrates from the tumor microenvironment (TME); …
might prefer “addicting” specific energy substrates from the tumor microenvironment (TME); …
RNA m6A demethylase FTO-mediated epigenetic up-regulation of LINC00022 promotes tumorigenesis in esophageal squamous cell carcinoma
Y Cui, C Zhang, S Ma, Z Li, W Wang, Y Li, Y Ma… - Journal of Experimental …, 2021 - Springer
Background Long non-coding RNA (LncRNA) controls cell proliferation and plays a
significant role in the initiation and progression of esophageal squamous cell carcinoma …
significant role in the initiation and progression of esophageal squamous cell carcinoma …
Genome-wide analysis of human long noncoding RNAs: a provocative review
CP Ponting, W Haerty - Annual review of genomics and human …, 2022 - annualreviews.org
Do long noncoding RNAs (lncRNAs) contribute little or substantively to human biology? To
address how lncRNA loci and their transcripts, structures, interactions, and functions …
address how lncRNA loci and their transcripts, structures, interactions, and functions …
Developmental dynamics of RNA translation in the human brain
The precise regulation of gene expression is fundamental to neurodevelopment, plasticity
and cognitive function. Although several studies have profiled transcription in the developing …
and cognitive function. Although several studies have profiled transcription in the developing …
Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques
L Santus, M Sopena-Rios, R García-Pérez… - Nature …, 2023 - nature.com
Long non-coding RNAs (lncRNAs) are involved in numerous biological processes and are
pivotal mediators of the immune response, yet little is known about their properties at the …
pivotal mediators of the immune response, yet little is known about their properties at the …
A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis
Inflammatory bowel diseases (IBD) are known to have complex, genetically influenced
etiologies, involving dysfunctional interactions between the intestinal immune system and …
etiologies, involving dysfunctional interactions between the intestinal immune system and …
Cross-regional homeostatic and reactive glial signatures in multiple sclerosis
T Trobisch, A Zulji, NA Stevens, S Schwarz… - Acta …, 2022 - Springer
Multiple sclerosis (MS) is a multifocal and progressive inflammatory disease of the central
nervous system (CNS). However, the compartmentalized pathology of the disease affecting …
nervous system (CNS). However, the compartmentalized pathology of the disease affecting …