Umbilical cord blood transplantation: the first 25 years and beyond

KK Ballen, E Gluckman… - Blood, The Journal of the …, 2013 - ashpublications.org
Umbilical cord blood is an alternative hematopoietic stem cell source for patients with
hematologic diseases who can be cured by allogeneic hematopoietic cell transplantation …

The European Society for Blood and Marrow Transplantation (EBMT) consensus guidelines for the detection and treatment of donor-specific anti-HLA antibodies (DSA …

SO Ciurea, K Cao, M Fernandez-Vina… - Bone marrow …, 2018 - nature.com
Haploidentical donors are now increasingly considered for transplantation in the absence of
HLA-matched donors or when an urgent transplant is needed. Donor-specific anti-HLA …

[HTML][HTML] Phase I/II trial of StemRegenin-1 expanded umbilical cord blood hematopoietic stem cells supports testing as a stand-alone graft

JE Wagner, CG Brunstein, AE Boitano, TE DeFor… - Cell stem cell, 2016 - cell.com
Clinical application of umbilical cord blood (UCB) as a source of hematopoietic stem cells for
transplantation is limited by low CD34+ cell dose, increased risk of graft failure, and slow …

Current concepts in the pathophysiology and treatment of aplastic anemia

NS Young, RT Calado, P Scheinberg - Blood, 2006 - ashpublications.org
Aplastic anemia, an unusual hematologic disease, is the paradigm of the human bone
marrow failure syndromes. Almost universally fatal just a few decades ago, aplastic anemia …

One-unit versus two-unit cord-blood transplantation for hematologic cancers

JE Wagner Jr, M Eapen, S Carter, Y Wang… - … England Journal of …, 2014 - Mass Medical Soc
Background Umbilical-cord blood has been used as the source of hematopoietic stem cells
in an estimated 30,000 transplants. The limited number of hematopoietic cells in a single …

Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on …

JE Wagner, JN Barker, TE DeFor… - Blood, The Journal …, 2002 - ashpublications.org
The potential benefits of unrelated donor marrow transplantation are offset by the
immunologic complications of graft-versus-host disease (GVHD) and infection. Therefore …

Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia

MJ Laughlin, M Eapen, P Rubinstein… - New England journal …, 2004 - Mass Medical Soc
Background Data regarding the outcome of cord-blood transplantation in adults are scant,
despite the fact that these grafts are increasingly used in adults. Methods We compared the …

Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood

CG Brunstein, JA Gutman, DJ Weisdorf… - Blood, The Journal …, 2010 - ashpublications.org
Effectiveness of double umbilical cord blood (dUCB) grafts relative to conventional marrow
and mobilized peripheral blood from related and unrelated donors has yet to be established …

Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study

M Eapen, P Rubinstein, MJ Zhang, C Stevens… - The Lancet, 2007 - thelancet.com
Background Although umbilical cord blood is an accepted alternative to bone marrow for
transplantation, allele-matched bone marrow is generally regarded as the preferred graft …

Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia

V Rocha, M Labopin, G Sanz, W Arcese… - … England Journal of …, 2004 - Mass Medical Soc
Background Promising results of cord-blood transplants from unrelated donors have been
reported in adults. Methods We compared outcomes in 682 adults with acute leukemia who …