Cell-free fetal DNA (cffDNA) extraction from whole blood by using a fully automatic centrifugal microfluidic device based on displacement of magnetic silica beads

A Hatami, M Saadatmand, M Garshasbi - Talanta, 2024 - Elsevier
The purpose of this research was to design a fully automated centrifugal microfluidic system
(Lab-on-a-Disk) for isolating cell free fetal DNAs (cffDNAs) from whole blood. To achieve this …

[HTML][HTML] Effective Boundary Correction for Deterministic Lateral Displacement Microchannels to Improve Cell Separation: A Numerical and Experimental Study

S Mirhosseini, M Eskandarisani, A Faghih Nasiri… - Biosensors, 2024 - mdpi.com
Particle separation and sorting techniques based on microfluidics have found extensive
applications and are increasingly gaining prominence. This research presents the design …

Microstructured Porous Capacitive Bio-pressure Sensor Using Droplet-based Microfluidics

M Eskandarisani, M Aliverdinia… - Journal of Medical …, 2024 - journals.lww.com
Background: Devices that mimic the functions of human skin are known as “electronic skin,”
and they must have characteristics like high sensitivity, a wide dynamic range, high spatial …

Machine Learning and Genetic Algorithms in the Microfluidic Design of Highly Efficient Micromixers

A Naseri Karimvand, M Amirmahani… - Industrial & …, 2024 - ACS Publications
Microscale reactions are often used to determine the reactivity and byproducts of
combinatorial reactions between diverse chemicals. Despite significant work in designing …

[HTML][HTML] Numerical investigation of centrifugal passive mixing in Omega shaped microchannel and comparison with fixed platform

AS Souderjani, R Dezhkam, A Shamloo… - Results in …, 2024 - Elsevier
The extraction of DNA from isolated cells is crucial for diagnosing and treating various
diseases, including cancer, which has become a leading cause of death in recent years …

Streamline-directed tunable deterministic lateral displacement chip: A numerical approach to efficient particle separation

AK Barzoki, A Shamloo - Journal of Chromatography A, 2024 - Elsevier
Abstract In conventional Deterministic Lateral Displacement (DLD), the migration behavior of
a particle of specific size is determined by the critical diameter (D c), which is predefined by …

Target cell lysis using magnetophoresis: A numerical study with experimental validation

R Dezhkam, M Topaheidari, Z Rostami, A Shamloo - Physics of Fluids, 2024 - pubs.aip.org
Cell lysis is one of the main steps in the deoxyribonucleic acid (DNA) extraction process,
which makes vital information about organisms accessible for analysis. In the chemical cell …

Lab-on-a-Disk Particle Separation Using a Novel Automated Slab Valve for Two-Step Filtration

R Dezhkam, E Pishbin, EA Moghaddam, A Rahi… - BioNanoScience, 2025 - Springer
Urological symptoms are usually accompanied by several etiologies; therefore, diagnosis is
often based on multiple tests, which include imaging and urine analysis, among others. One …

A numerical modeling study on the impact of particle concentration on the particle sorting in spiral channels

AD Van, VS Pham - Physics of Fluids, 2024 - pubs.aip.org
This work investigates the influence of concentration on the separation of microparticles in
spiral microchannels. Using numerical modeling, we study the impact of the particle …

Streamline-Directed Tunable Deterministic Lateral Displacement (DLD) Chip: A Novel Approach to Efficient Particle Separation

AK Barzoki, A Shamloo - arXiv preprint arXiv:2401.08359, 2024 - arxiv.org
In conventional Deterministic Lateral Displacement (DLD), the migration behavior of a
particle of specific size is determined by the critical diameter (Dc), which is predefined by the …