Emerging roles of tRNA-derived fragments in cancer
M Fu, J Gu, M Wang, J Zhang, Y Chen, P Jiang, T Zhu… - Molecular cancer, 2023 - Springer
Abstract tRNA-derived fragments (tRFs) are an emerging category of small non-coding
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …
Action mechanisms and research methods of tRNA-derived small RNAs
Y Xie, L Yao, X Yu, Y Ruan, Z Li, J Guo - Signal transduction and …, 2020 - nature.com
Abstract tRNA-derived small RNAs (tsRNAs), including tRNA-derived fragments (tRFs) and
tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or …
tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or …
RNAInter v4. 0: RNA interactome repository with redefined confidence scoring system and improved accessibility
Establishing an RNA-associated interaction repository facilitates the system-level
understanding of RNA functions. However, as these interactions are distributed throughout …
understanding of RNA functions. However, as these interactions are distributed throughout …
Noncanonical roles of tRNAs: tRNA fragments and beyond
As one of the most abundant and conserved RNA species, transfer RNAs (tRNAs) are well
known for their role in reading the codons on messenger RNAs and translating them into …
known for their role in reading the codons on messenger RNAs and translating them into …
TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer
RNA modifications are important regulatory elements of RNA functions. However, most
genome-wide mapping of RNA modifications has focused on messenger RNAs and transfer …
genome-wide mapping of RNA modifications has focused on messenger RNAs and transfer …
tRNA fragments (tRFs) guide Ago to regulate gene expression post-transcriptionally in a Dicer-independent manner
tRNA related RNA fragments (tRFs), also known as tRNA-derived RNAs (tdRNAs), are
abundant small RNAs reported to be associated with Argonaute proteins, yet their function is …
abundant small RNAs reported to be associated with Argonaute proteins, yet their function is …
tRNA-derived RNA fragments in cancer: current status and future perspectives
Non-coding RNAs (ncRNAs) have been the focus of many studies over the last few decades,
and their fundamental roles in human diseases have been well established. Transfer RNAs …
and their fundamental roles in human diseases have been well established. Transfer RNAs …
On the expanding roles of tRNA fragments in modulating cell behavior
R Magee, I Rigoutsos - Nucleic acids research, 2020 - academic.oup.com
The fragments that derive from transfer RNAs (tRNAs) are an emerging category of
regulatory RNAs. Known as tRFs, these fragments were reported for the first time only a …
regulatory RNAs. Known as tRFs, these fragments were reported for the first time only a …
Roles and regulation of tRNA-derived small RNAs in animals
S Muthukumar, CT Li, RJ Liu, C Bellodi - Nature Reviews Molecular Cell …, 2024 - nature.com
A growing class of small RNAs, known as tRNA-derived RNAs (tdRs), tRNA-derived small
RNAs or tRNA-derived fragments, have long been considered mere intermediates of tRNA …
RNAs or tRNA-derived fragments, have long been considered mere intermediates of tRNA …
tRNA-derived small RNA: a novel regulatory small non-coding RNA
S Li, Z Xu, J Sheng - Genes, 2018 - mdpi.com
Deep analysis of next-generation sequencing data unveils numerous small non-coding
RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA …
RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA …