Advancing cell therapy for neurodegenerative diseases
S Temple - Cell Stem Cell, 2023 - cell.com
Cell-based therapies are being developed for various neurodegenerative diseases that
affect the central nervous system (CNS). Concomitantly, the roles of individual cell types in …
affect the central nervous system (CNS). Concomitantly, the roles of individual cell types in …
Hematopoietic stem cell transplantation and cellular therapies for autoimmune diseases: overview and future considerations from the Autoimmune Diseases Working …
T Alexander, R Greco - Bone marrow transplantation, 2022 - nature.com
Autoimmune diseases (ADs) represent a heterogenous group of complex diseases with
increasing incidence in Western countries and are a major cause of morbidity …
increasing incidence in Western countries and are a major cause of morbidity …
The current standing of autologous haematopoietic stem cell transplantation for the treatment of multiple sclerosis
AG Willison, T Ruck, G Lenz, HP Hartung… - Journal of neurology, 2022 - Springer
Autologous haematopoietic stem cell transplantation (aHSCT) is gaining traction as a
valuable treatment option for patients affected by severe multiple sclerosis (MS), particularly …
valuable treatment option for patients affected by severe multiple sclerosis (MS), particularly …
Autologous hematopoietic stem-cell transplantation in multiple sclerosis: a systematic review and meta-analysis
Introduction In 1995, the use of autologous hematopoietic stem-cell transplantation
(AHSCT), which was previously used to treat hematological tumors, was introduced for …
(AHSCT), which was previously used to treat hematological tumors, was introduced for …
[HTML][HTML] Antibody-mediated cell depletion therapies in multiple sclerosis
A Mariottini, PA Muraro, JD Lünemann - Frontiers in Immunology, 2022 - frontiersin.org
Development of disease-modifying therapies including monoclonal antibody (mAb)-based
therapeutics for the treatment of multiple sclerosis (MS) has been extremely successful over …
therapeutics for the treatment of multiple sclerosis (MS) has been extremely successful over …
Correlation between the Neutrophil‐to‐Lymphocyte Ratio and Multiple Sclerosis: Recent Understanding and Potential Application Perspectives
Q Zhou, R Jia, J Dang - Neurology Research International, 2022 - Wiley Online Library
Multiple sclerosis (MS) is a chronic debilitating immune‐mediated disease of the central
nervous system, which causes demyelination and neuroaxonal damage. Low‐grade …
nervous system, which causes demyelination and neuroaxonal damage. Low‐grade …
[HTML][HTML] Hematopoietic stem cell transplantation for neurological disorders: A focus on inborn errors of metabolism
P de Vasconcelos, JF Lacerda - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Hematopoietic stem cells have been investigated and applied for the treatment of certain
neurological disorders for a long time. Currently, their therapeutic potential is harnessed in …
neurological disorders for a long time. Currently, their therapeutic potential is harnessed in …
Current knowledge on multiple sclerosis pathophysiology, disability progression assessment and treatment options, and the role of autologous hematopoietic stem …
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that
affects nearly 2.8 million people each year. MS distinguishes three main types: relapsing …
affects nearly 2.8 million people each year. MS distinguishes three main types: relapsing …
Cellular-based therapies in systemic sclerosis: from hematopoietic stem cell transplant to innovative approaches
E Xue, A Minniti, T Alexander, N Del Papa, R Greco… - Cells, 2022 - mdpi.com
Systemic sclerosis (SSc) is a systemic disease characterized by autoimmune responses,
vasculopathy and tissue fibrosis. The pathogenic mechanisms involve a wide range of cells …
vasculopathy and tissue fibrosis. The pathogenic mechanisms involve a wide range of cells …
Impact of autologous HSCT on the quality of life and fatigue in patients with relapsing multiple sclerosis
N Giedraitiene, G Gasciauskaite, G Kaubrys - Scientific reports, 2022 - nature.com
In this study, we aimed to assess the quality of life, fatigue, anxiety, and depression after
Autologous haematopoietic stem cell transplantation (AHSCT) and to investigate its impact …
Autologous haematopoietic stem cell transplantation (AHSCT) and to investigate its impact …