Aim: Hyperuricemia as a putative risk factor for chronic kidney disease (CKD) progression
remains controversial and debatable. This systematic review aims to explore the prevalence …

Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues
and dying cells which, when crystalized, is able to activate the NLRP3 inflammasome …

Hyperuricemia and gout are metabolic diseases characterized with high serum urate and
impact human health significantly. Although some drugs have been developed to treat gout …

Background Non-alcoholic fatty liver disease (NAFLD), recognized as the liver manifestation
of metabolic syndrome, is highly prevalent in the general population. Recent studies suggest …

Background Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease
worldwide, and its prevalence is likely to rise even further. To help understand the …

Abstract Background: In Brazil, population-based researches analyzing prevalence and
factors associated with metabolic syndrome (MS), a recognized predictor of cardiovascular …

Background Serum uric acid (SUA) and oxidized LDL (oxLDL) may be associated with
arterial aging. The aim of our study was to evaluate the relationship between SUA, oxLDL …

Resumo Fundamento: No Brasil, são escassas as investigações de base populacional
analisando a prevalência e os fatores associados à síndrome metabólica (SM), reconhecida …

Abstract Background/Aims: Evidence indicates a role for dyslipidemia in the development of
chronic kidney disease (CKD). However, the association of lipid abnormalities and their …

The pathogenesis of hyperuricemia-induced chronic kidney disease is largely unknown. In
this study, we investigated whether extracellular signal–regulated kinases1/2 (ERK1/2) …