The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …

This review focuses on cytotoxic rhenium compounds in terms of IC 50 values, their mode of
action in biological systems and their status in clinical trials. Biological studies of different …

In the recent years, organometallic compounds have become recognized as promising anti-
cancer drug candidates. While radioactive 186/188Re compounds are already used in …

Our work has shown that certain ruthenium (II) arene complexes exhibit promising
anticancer activity in vitro and in vivo. The complexes are stable and water-soluble, and their …

Combination therapy targeting both tumor growth and vascularization is considered to be a
cornerstone for colorectal carcinomas (CRC) treatment. However, the major obstacles of …

Rhenium (V) oxo complexes of general formula [ReO (OMe)(N^ N) Cl2], where N^ N= 4, 7-
diphenyl-1, 10-phenanthroline, 1, or 3, 4, 7, 8-tetramethyl-1, 10-phenanthroline, 2, effectively …

The photophysical properties of [Re (CO) 3 (l‐N3)] Br (l‐N3= 2‐azido‐N, N‐bis [(quinolin‐2‐
yl) methyl] ethanamine), which could not be localized in cancer cells by fluorescence …

Modified Mannich reactions of amines, amino acids and a model peptide with Ph2PH and
CH2O gave bis (diphenylphosphinomethyl) amines (Ph2PCH2) 2NR [R= Ph (1) …

Cancer is one of the deadliest diseases worldwide. Chemotherapy remains one of the most
dominant forms for anticancer treatment. Despite their clinical success, the used …

To study the interaction of the fac-[M (CO) 3]+ moiety (M= 99mTc, 188Re) with DNA bases,
we reacted [M (OH2) 3 (CO) 3]+ with 9-methylguanine (9-MeG), guanosine (G), and 2 …