Intracellular calcium signaling is a universal language source shared by the most part of
biological entities inside cells that, all together, give rise to physiological and functional …

17β-Estradiol (E2) is the main estrogenic hormone in the body and exerts many
cardiovascular protective effects. Via three receptors known to date, including estrogen …

Background Increased neutrophil infiltration and the ensuing inflammatory response
represent a hallmark event in cardiac ischemia-reperfusion injury (IRI). It remains poorly …

Abstract Plasma membrane Ca 2+ transport ATPases (PMCA1-4, ATP2B1-4) are
responsible for removing excess Ca 2+ from the cell in order to keep the cytosolic Ca 2+ ion …

Introduction: Erythropoietin (EPO) acts primarily in regulating red blood cell production
mediated by high EPO receptor (EPOR) expression in erythroid progenitor cells. EPO activity …

Neurological diseases are expected to become the leading cause of death in the next
decade. Although little is known about it, the interaction between oxidative stress and …

Duchenne muscular dystrophy (DMD) is a progressive disease characterized by skeletal
muscle atrophy, respiratory failure, and cardiomyopathy. Our previous studies have shown …

Introduction Despite decades of improved strategy in conventional cardiopulmonary
resuscitation (CCPR), survival rates of favorable neurological outcome after cardiac arrest …

Ischaemic heart disease is the world's leading cause of mortality. Survival rates from acute
myocardial infarction (MI) have improved in recent years; however, this has led to an …

Chronic heart failure is a serious, progressive pathology with a rising prevalence and a
mortality rate that has not improved in several decades. A new potential treatment strategy is …