An updated overview of cyclodextrin-based drug delivery systems for cancer therapy

DN Păduraru, AG Niculescu, A Bolocan, O Andronic… - Pharmaceutics, 2022 - mdpi.com
Encompassing a group of complex and heterogeneous diseases, cancer continues to be a
challenge for patients and healthcare systems worldwide. Thus, it is of vital importance to …

Cyclodextrin nanoparticles for diagnosis and potential cancer therapy: A systematic review

A Karthic, A Roy, J Lakkakula, S Alghamdi… - Frontiers in Cell and …, 2022 - frontiersin.org
Cancer is still one of the world's deadliest health concerns. As per latest statistics, lung,
breast, liver, prostate, and cervical cancers are reported topmost worldwide. Although …

Application of cyclodextrin for Cancer Immunotherapy

X Wei, CY Yu, H Wei - Molecules, 2023 - mdpi.com
Tumor immunotherapy, compared with other treatment strategies, has the notable
advantage of a long-term therapeutic effect for preventing metastasis and the recurrence of …

Prospects of charged cyclodextrins in biomedical applications

V Sehgal, SP Pandey, PK Singh - Carbohydrate Polymers, 2024 - Elsevier
Cyclodextrins (CDs), recognized for their unique ability to form inclusion complexes, have
seen broad utilization across various scientific fields. Recently, there has been a surge of …

[HTML][HTML] Cyclodextrin modified with different groups to enhance the drug delivery efficiency of gold nanoparticles to treat cancer

CH Nguyen, KS Banh, TNM An, NTH Anh… - Arabian Journal of …, 2023 - Elsevier
The aim of this research is to investigate the influence of different functional groups of β-
cyclodextrin (CD) in functionalizing gold nanoparticles. The functionalized nanoparticles are …

Chitosan and Cyclodextrins—Versatile Materials Used to Create Drug Delivery Systems for Gastrointestinal Cancers

A Najm, AG Niculescu, A Bolocan, M Rădulescu… - Pharmaceutics, 2023 - mdpi.com
Gastrointestinal cancers are characterized by a frequent incidence, a high number of
associated deaths, and a tremendous burden on the medical system and patients …

Cyclodextrin based nanoparticles for smart drug delivery in colorectal cancer

D Marabada, J Li, S Wei, Q Huang… - Chemical Biology & …, 2023 - Wiley Online Library
The advancement of colorectal cancer (CRC) prevention, detection, and treatment is
essential to ensure that survivors live longer and higher‐quality lives. The field of cancer …

Insights into recent preclinical studies on labelled cyclodextrin-based imaging probes: Towards a novel oncological era

Z Képes, I Hajdu, F Fenyvesi, G Trencsényi - International Journal of …, 2023 - Elsevier
As malignancies remain one of the major health concerns worldwide, increasing focus has
been centered around the application of cyclodextrins (CDs) in cancer imaging and therapy …

Synergistic antitumor potency of a self-assembling cyclodextrin nanoplex for the co-delivery of 5-fluorouracil and interleukin-2 in the treatment of colorectal cancer

S Akkın, G Varan, A Işık, S Gökşen, E Karakoç… - Pharmaceutics, 2023 - mdpi.com
Chemotherapy is the most used method after surgery in the treatment of colon cancer.
Cancer cells escape the recognition mechanism of immune system cells to survive and …

IL-2 based cancer immunotherapies: an evolving paradigm

S Rokade, AM Damani, M Oft, J Emmerich - Frontiers in Immunology, 2024 - frontiersin.org
Discovered over 4 decades ago in the supernatants of activated T cells, interleukin-2 (IL-2)
is a potent pleiotropic cytokine involved in the regulation of immune responses. It is required …