Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
Human genetics and malaria resistance
SN Kariuki, TN Williams - Human genetics, 2020 - Springer
Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …
throughout much of the last five thousand years and, as a result, it is the strongest force for …
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
J Gruszczyk, U Kanjee, LJ Chan, S Menant, B Malleret… - Science, 2018 - science.org
Plasmodium vivax shows a strict host tropism for reticulocytes. We identified transferrin
receptor 1 (TfR1) as the receptor for P. vivax reticulocyte-binding protein 2b (PvRBP2b). We …
receptor 1 (TfR1) as the receptor for P. vivax reticulocyte-binding protein 2b (PvRBP2b). We …
A research agenda for malaria eradication: vaccines
malERA Consultative Group on Vaccines - PLoS medicine, 2011 - journals.plos.org
Vaccines could be a crucial component of efforts to eradicate malaria. Current attempts to
develop malaria vaccines are primarily focused on Plasmodium falciparum and are directed …
develop malaria vaccines are primarily focused on Plasmodium falciparum and are directed …
The future for blood‐stage vaccines against malaria
JS Richards, JG Beeson - Immunology and cell biology, 2009 - Wiley Online Library
Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …
The immunology of Plasmodium vivax malaria
Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America,
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …
Human genetics of infectious diseases: Unique insights into immunological redundancy
JL Casanova, L Abel - Seminars in immunology, 2018 - Elsevier
For almost any given human-tropic virus, bacterium, fungus, or parasite, the clinical outcome
of primary infection is enormously variable, ranging from asymptomatic to lethal infection …
of primary infection is enormously variable, ranging from asymptomatic to lethal infection …
Blood groups and malaria: fresh insights into pathogenesis and identification of targets for intervention
JA Rowe, DH Opi, TN Williams - Current opinion in hematology, 2009 - journals.lww.com
Blood groups and malaria: fresh insights into pathogenesis a... : Current Opinion in Hematology
Blood groups and malaria: fresh insights into pathogenesis and identification of targets for …
Blood groups and malaria: fresh insights into pathogenesis and identification of targets for …
Designing an effective malaria vaccine targeting Plasmodium vivax Duffy-binding protein
Malaria caused by the Plasmodium vivax parasite is a major global health burden. Immunity
against blood-stage infection reduces parasitemia and disease severity. Duffy-binding …
against blood-stage infection reduces parasitemia and disease severity. Duffy-binding …
A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax
B Russell, R Suwanarusk, C Borlon… - Blood, The Journal …, 2011 - ashpublications.org
Currently, there are no reliable RBC invasion assays to guide the discovery of vaccines
against Plasmodium vivax, the most prevalent malaria parasite in Asia and South America …
against Plasmodium vivax, the most prevalent malaria parasite in Asia and South America …