▪ Abstract Apoptosis of mature T lymphocytes preserves peripheral homeostasis and
tolerance by countering the profound changes in the number and types of T cells stimulated …

AIDS, caused by the retroviruses human immunodeficiency virus type 1 and type 2 (HIV-1
and HIV-2), has reached pandemic proportions. Therefore, it is critical to understand how …

Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms
involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized …

This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Background: A highly sensitive, fast, and simple flow cytometric assay to assess human red
blood cell (RBCs) viability and aging is reported. Methods: The assay described in this …

Infection with the human immunodeficiency virus (HIV) is associated with a progressive
decrease in CD4 T-cell number and a consequent impairment in host immune defenses …

Introduction Immunological damage in acute HIV infection (AHI) may predispose to
detrimental clinical sequela. However, studies on the earliest HIV-induced immunological …

Abstract The Bcg/Nramp1 gene controls early resistance and susceptibility of macrophages
to mycobacterial infections. We previously reported that Mycobacterium tuberculosis …

The death-inducing receptor Fas is activated when cross-linked by the type II membrane
protein Fas ligand (FasL). When human soluble FasL (sFasL, containing the extracellular …

Viruses have evolved numerous mechanisms to evade the host immune system and one of
the strategies developed by HIV is to activate apoptotic programmes that destroy immune …