Specific activation of mitogen-activated protein kinase by transforming growth factor-β receptors in lipid rafts is required for epithelial cell plasticity

W Zuo, YG Chen - Molecular biology of the cell, 2009 - Am Soc Cell Biol
Transforming growth factor (TGF)-β regulates a spectrum of cellular events, including cell
proliferation, differentiation, and migration. In addition to the canonical Smad pathway, TGF …

Idiopathic pulmonary fibrosis: treatment update

OJ O'Connell, MP Kennedy, MT Henry - Advances in therapy, 2011 - Springer
Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial
pneumonias. Despite multiple recent clinical trials, there is no strong evidence supporting a …

[PDF][PDF] Therapeutic effect of magnesium isoglycyrrhizinate in rats on lung injury induced by paraquat poisoning

ZW Xiao, W Zhang, L Ma, ZW Qiu - Eur Rev Med Pharmacol Sci, 2014 - europeanreview.org
OBJECTIVE: The aim of this study was to investigate the effect of Magnesium
Isoglycyrrhizinate (MgIG) on intercellular adhesion moledule-1 (ICAM-1) and matrix …

Reduced number of endothelial progenitor cells is predictive of early relapse in anti-neutrophil cytoplasmic antibody-associated vasculitis

J Zavada, L Kideryova, R Pytlík, Z Hrušková… - …, 2009 - academic.oup.com
Objectives. ANCA-associated vasculitis (AAV) is an inflammatory disorder of small-to
medium-sized vessels with relapsing/remitting progression. Microvascular endothelial injury …

Медикаментозное управление окислительно-восстановительным состоянием организма при заболеваниях органов дыхания (часть 6)

АЕ Абатуров, АП Волосовец, ТП Борисова - Здоровье ребенка, 2018 - cyberleninka.ru
Медикаментозное управление окислительно-восстановительным состоянием организма
при заболеваниях органов дыхания (часть 6) – тема научной статьи по фундаментальной …

NO-releasing xanthine KMUP-1 bonded by simvastatin attenuates bleomycin-induced lung inflammation and delayed fibrosis

CP Liu, MS Kuo, BN Wu, CY Chai, HT Huang… - Pulmonary …, 2014 - Elsevier
Background and purpose Pulmonary fibrosis (PF) is a progressing lung injury initiated by
pulmonary inflammation (PI). Bleomycin (BLM) is the most common pathogenesis of PF …

[PDF][PDF] 阿托伐他汀对肺纤维化大鼠MMP-9 和TIMP-1 表达的影响

刘斌, 张玉华, 魏路清, 李振华 - 基础医学与临床, 2011 - journal11.magtechjournal.com
有文献表明, 他1 类药物可通过抑制基质金属蛋白酶, 干预成纤维细胞增殖, 胶原合成,
参与调节细胞外基质(ex tracelluarmatrix, ECM) 的降解, 可能具有抗纤维化作用[1] …

[HTML][HTML] 阿托伐他汀钙对百草枯致肺纤维化大鼠MMP-9 及TIMP-1 表达的影响

高娟, 韩茹, 任丽萍 - 中国辐射卫生, 2016 - html.rhhz.net
目的探讨阿托伐他汀钙对百草枯致肺纤维化大鼠MMP-9 及TIMP-1 表达的影响. 方法45 只SPF
级雄性Wister 大鼠, 随机分为3 组, 正常对照组, 百草枯组(模型组), 阿托伐他汀干预组(治疗组) …

Circulating endothelial progenitor cells in ANCA-associated vasculitis: the light at the end of the tunnel?

ANC Santana - Rheumatology, 2009 - academic.oup.com
The main clinical features of ANCA-associated vasculitis (AAV) are inflammation and
necrosis of small vessels, thrombus formation and endothelial injury [1–3]. In this issue of …

Interstitial lung diseases: the role of HRCT in in the era of antifibrotic therapy

ANC Santana, FSN Soares - Jornal Brasileiro de Pneumologia, 2020 - SciELO Brasil
Interstitial lung diseases (ILD) typically represent a major challenge for pulmonologists. That
challenge has various facets, such as defining the diagnosis, searching for a possible …