Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury

H Zhao, JS Perez, K Lu… - American Journal of …, 2014 - journals.physiology.org
Toll-like receptor-4 (TLR-4) has been increasingly recognized as playing a critical role in the
pathogenesis of ischemia-reperfusion injury (IRI) of renal grafts. This review provides a …

The diverse biological properties of the chemically inert noble gases

DA Winkler, A Thornton, G Farjot, I Katz - Pharmacology & therapeutics, 2016 - Elsevier
The noble gases represent an intriguing scientific paradox. They are extremely inert
chemically but display a remarkable spectrum of clinically useful biological properties …

[HTML][HTML] Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats

H Zhao, J Ning, A Lemaire, FS Koumpa, JJ Sun… - Kidney international, 2015 - Elsevier
Early renal graft injury could result in remote pulmonary injury due to kidney–lung cross talk.
Here we studied the possible role of regulated necrosis in remote lung injury in a rat …

Heme Oxygenase-1-Expressing Dendritic Cells Promote Foxp3+ Regulatory T Cell Differentiation and Induce Less Severe Airway Inflammation in Murine Models

TH Wong, HA Chen, RJ Gau, JH Yen, JL Suen - PloS one, 2016 - journals.plos.org
Dendritic cells (DCs) are critical for instructing immune responses toward inflammatory or
anti-inflammatory status. Heme oxygenase-1 (HO-1) is known for its cytoprotective effect …

Ferulic Acid Protected from Kidney Ischemia Reperfusion Injury in Mice: Possible Mechanism Through Increasing Adenosine Generation via HIF-1α

Q Zhou, X Gong, G Kuang, R Jiang, T Xie, HT Tie… - Inflammation, 2018 - Springer
Ferulic acid (FA), derived from fruits and vegetables, is well-known as a potent antioxidant of
scavenging free radicals. However, the role and underlying mechanism of FA on kidney …

The efficacy of noble gases in the attenuation of ischemia reperfusion injury: a systematic review and meta-analyses

J De Deken, S Rex, D Monbaliu, J Pirenne… - Critical Care …, 2016 - journals.lww.com
Objective: Noble gases have been attributed to organ protective effects in ischemia
reperfusion injury in a variety of medical conditions, including cerebral and cardiac …

Antiapoptotic activity of argon and xenon

S Spaggiari, O Kepp, S Rello-Varona, K Chaba… - Cell cycle, 2013 - Taylor & Francis
Although chemically non-reactive, inert noble gases may influence multiple physiological
and pathological processes via hitherto uncharacterized physical effects. Here we report a …

Ischemic postconditioning attenuates acute kidney injury following intestinal ischemia‐reperfusion through Nrf2‐regulated autophagy, anti‐oxidation, and anti …

R Chen, Z Zeng, Y Zhang, C Cao, H Liu, W Li… - The FASEB …, 2020 - Wiley Online Library
Intestinal ischemia‐reperfusion (IIR) often occurs during and following major cardiovascular
or gut surgery and causes significant organ including kidney injuries. This study was to …

The role of heme oxygenase-1 in remote ischemic and anesthetic organ conditioning

I Bauer, A Raupach - Antioxidants, 2019 - mdpi.com
The cytoprotective effects of the heme oxygenase (HO) pathway are widely acknowledged.
These effects are mainly mediated by degradation of free, pro-oxidant heme and the …

Noble gases as cardioprotectants–translatability and mechanism

KF Smit, NC Weber, MW Hollmann… - British journal of …, 2015 - Wiley Online Library
Several noble gases, although classified as inert substances, exert a tissue‐protective effect
in different experimental models when applied before organ ischaemia as an early or late …