Primary nonresponse and primary nonremission are important limitations of tumor necrosis
factor (TNF) antagonists, occurring in 10% to 40% and 50% to 80% of patients with …

Background Crohn's disease (CD) is a chronic disabling and progressive IBD. Only
strategies looking beyond symptoms and based on tight monitoring of objective signs of …

Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

1.1. Термины и определение Болезнь Крона (БК)–хроническое, рецидивирующее
заболевание желудочно-кишечного тракта неясной этиологии, характеризующееся …

This paper is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management …

Summary Background Most patients with Crohn's disease need an intestinal resection, but a
majority will subsequently experience disease recurrence and require further surgery. This …

Background & Aims Most patients with Crohn's disease (CD) eventually require an intestinal
resection. However, CD frequently recurs after resection. We performed a randomized trial to …

Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

OBJECTIVES: Postsurgical recurrence of Crohn's disease (CD) is very frequent and, to date,
only infliximab has been shown to be useful in preventing it. The efficacy of adalimumab …

Although the number of available therapies for the treatment of ulcerative colitis and Crohn's
disease (CD) continues to expand, a significant portion of patients with inflammatory bowel …