[HTML][HTML] Tumor energy metabolism and potential of 3-bromopyruvate as an inhibitor of aerobic glycolysis: implications in tumor treatment

T Fan, G Sun, X Sun, L Zhao, R Zhong, Y Peng - Cancers, 2019 - mdpi.com
Tumor formation and growth depend on various biological metabolism processes that are
distinctly different with normal tissues. Abnormal energy metabolism is one of the typical …

[HTML][HTML] Diverse stakeholders of tumor metabolism: an appraisal of the emerging approach of multifaceted metabolic targeting by 3-bromopyruvate

S Yadav, SK Pandey, Y Goel, MK Temre… - Frontiers in …, 2019 - frontiersin.org
Malignant cells possess a unique metabolic machinery to endure unobstructed cell survival.
It comprises several levels of metabolic networking consisting of 1) upregulated expression …

Nimbolide induces cell death in T lymphoma cells: Implication of altered apoptosis and glucose metabolism

PK Jaiswara, VK Gupta, P Sonker… - Environmental …, 2021 - Wiley Online Library
Nimbolide is a tetranortriterpenoid derived from the leaves and flowers of Azadirachta indica
(Neem). It exhibits anticancer activity against a variety of cancers by modulating various …

Nimbolide retards T cell lymphoma progression by altering apoptosis, glucose metabolism, pH regulation, and ROS homeostasis

PK Jaiswara, A Kumar - Environmental Toxicology, 2022 - Wiley Online Library
Nimbolide is reported as one of the potential anticancer candidates of the neem tree
(Azadirachta indica A. Juss). The cytotoxic action of nimbolide has been well reported …

[HTML][HTML] Tumor Decelerating and Chemo-Potentiating Action of Methyl Jasmonate on a T Cell Lymphoma In Vivo: Role of Altered Regulation of Metabolism, Cell …

Y Goel, S Yadav, SK Pandey, MK Temre… - Frontiers in …, 2021 - frontiersin.org
Methyl jasmonate (MJ), a natural oxylipin, possesses a broad spectrum of antineoplastic
potential in vitro. However, its tumor growth impeding and chemo-potentiating action has not …

[HTML][HTML] Construction and evaluation of folic acid-modified 3-bromopyruvate cubosomes

F Hou, H Wang, Y Zhang, N Zhu, H Liu… - Medical Science Monitor …, 2020 - ncbi.nlm.nih.gov
Background Direct 3-bromopyruvate chemotherapy often causes side effects. We thus
aimed to construct and evaluate folic acid-modified 3-bromopyruvate liquid crystalline …

[HTML][HTML] Protective and recuperative effects of 3-bromopyruvate on immunological, hepatic and renal homeostasis in a murine host bearing ascitic lymphoma …

S Yadav, SK Pandey, Y Goel, PK Kujur… - Biomedicine & …, 2018 - Elsevier
bromopyruvate (3-BP) possesses promising antineoplastic potential, however, its effects on
immunological homeostasis vis a vis hepatic and renal functions in a tumor bearing host …

Cytotoxic action of acetate on tumor cells of thymic origin: role of MCT-1, pH homeostasis and altered cell survival regulation

SK Pandey, S Yadav, Y Goel, SM Singh - Biochimie, 2019 - Elsevier
Neoplastic cells display altered biosynthetic and bioenergetic machinery to support cell
survival. Therefore, cancer cells optimally utilize all available fuel resources to pump their …

[HTML][HTML] Methyl Jasmonate Cytotoxicity and Chemosensitization of T Cell Lymphoma In Vitro Is Facilitated by HK 2, HIF-1α, and Hsp70: Implication of Altered …

Y Goel, S Yadav, SK Pandey, MK Temre… - Frontiers in …, 2021 - frontiersin.org
Methyl jasmonate (MJ) displays antineoplastic potential against numerous neoplastic cells.
However, several mechanistic aspects of its antineoplastic action against malignancies of T …

Aptamer-guided Selective Delivery of Therapeutics to Breast Cancer Cells Expressing Specific Biomarkers

SK Pandey, M Parul… - Current Cancer Therapy …, 2024 - ingentaconnect.com
Cancer biomarkers or tumor-associated antigens (TAA) are the focus area of current
research in cancer biology for diagnosis, prognosis, screening, and targeted treatments …