[HTML][HTML] Ocular drug delivery to the retina: current innovations and future perspectives

HM Kim, SJ Woo - Pharmaceutics, 2021 - mdpi.com
Treatment options for retinal diseases, such as neovascular age-related macular
degeneration, diabetic retinopathy, and retinal vascular disorders, have markedly expanded …

[HTML][HTML] Recent advances of ocular drug delivery systems: prominence of ocular implants for chronic eye diseases

M Mostafa, A Al Fatease, RG Alany, H Abdelkader - Pharmaceutics, 2023 - mdpi.com
Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …

Progress in nanomedicine-based drug delivery in designing of chitosan nanoparticles for cancer therapy

MZ Ahmad, M Rizwanullah, J Ahmad… - … Journal of Polymeric …, 2022 - Taylor & Francis
Cancer is among the most dreadful fatal diseases globally, and the efficacy of recent
chemotherapeutic approaches is limited due to many related drawbacks. The major …

Anti-angiogenic carbon nanovesicles loaded with bevacizumab for the treatment of age-related macular degeneration

A Anand, HJ Jian, HH Huang, LE Hean, YJ Li, JY Lai… - Carbon, 2023 - Elsevier
Intraocular angiogenesis mediated by vascular endothelial growth factor (VEGF) and the
related ocular disease, age-related macular degeneration (AMD), is the leading cause of …

[HTML][HTML] Nanodelivery of resveratrol-loaded PLGA nanoparticles for age-related macular degeneration

P Bhatt, G Fnu, D Bhatia, A Shahid, V Sutariya - AAPS PharmSciTech, 2020 - Springer
Age-related macular degeneration, precisely neovascular form, is the leading cause of
vision loss and the key treatment includes intravitreal injections of anti-vascular endothelial …

[HTML][HTML] Boosting the anticancer activity of sunitinib malate in breast cancer through lipid polymer hybrid nanoparticles approach

MM Ahmed, MK Anwer, F Fatima, MF Aldawsari… - Polymers, 2022 - mdpi.com
In the current study, lipid-polymer hybrid nanoparticles (LPHNPs) fabricated with lipoid-90H
and chitosan, sunitinib malate (SM), an anticancer drug was loaded using lecithin as a …

Emerging therapies and their delivery for treating age‐related macular degeneration

CN Thomas, DA Sim, WH Lee… - British journal of …, 2022 - Wiley Online Library
Age‐related macular degeneration (AMD) is the most common cause of blindness in the
Western world and is characterised in its latter stages by retinal cell death and …

[HTML][HTML] Pluronic F-127/silk fibroin for enhanced mechanical property and sustained release drug for tissue engineering biomaterial

J Youn, JH Choi, S Lee, SW Lee, BK Moon, JE Song… - Materials, 2021 - mdpi.com
Herein, an injectable thermosensitive hydrogel was developed for a drug and cellular
delivery system. The composite was prepared by facile physical mixing of pluronic F-127 …

Disease progression pathways of wet AMD: opportunities for new target discovery

AT Wolf, A Harris, F Oddone, B Siesky… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Age-related macular degeneration (AMD) is the leading cause of irreversible
blindness among people age 60 years or older in developed countries. Current standard-of …

Long-acting formulation strategies for protein and peptide delivery in the treatment of PSED

A Garkal, P Bangar, A Rajput, P Pingale, N Dhas… - Journal of Controlled …, 2022 - Elsevier
The invigoration of protein and peptides in serious eye disease includes age-related
macular degeneration, choroidal neovascularization, retinal neovascularization, and …