Health benefits of resveratrol: Evidence from clinical studies

AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Inflammation and oxidative stress in chronic kidney disease—potential therapeutic role of minerals, vitamins and plant-derived metabolites

SF Rapa, BR Di Iorio, P Campiglia, A Heidland… - International journal of …, 2019 - mdpi.com
Chronic kidney disease (CKD) is a debilitating pathology with various causal factors,
culminating in end stage renal disease (ESRD) requiring dialysis or kidney transplantation …

Antioxidant activity, total phenolics and flavonoids contents: Should we ban in vitro screening methods?

D Granato, F Shahidi, R Wrolstad, P Kilmartin… - Food chemistry, 2018 - Elsevier
As many studies are exploring the association between ingestion of bioactive compounds
and decreased risk of non-communicable diseases, the scientific community continues to …

Mitochondrial dysfunction in diabetic kidney disease

JM Forbes, DR Thorburn - Nature Reviews Nephrology, 2018 - nature.com
Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

Anti-inflammatory activity of natural stilbenoids: A review

M Dvorakova, P Landa - Pharmacological Research, 2017 - Elsevier
Resveratrol and other natural stilbenoids, including piceatannol, pterostilbene, and gnetol,
are well-known anti-inflammatory compounds with indisputable activity in vitro as well as in …

The effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease

A Hoseini, G Namazi, A Farrokhian, Ž Reiner… - Food & function, 2019 - pubs.rsc.org
This study was performed to investigate the effects of resveratrol on metabolic status in
patients with type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). This …

Inflammation, NF-κB, and chronic diseases: how are they linked?

AB Kunnumakkara, B Shabnam, S Girisa… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Most chronic diseases, caused by lifestyle factors, appear to be linked to inflammation.
Inflammation is activated mechanistically, and nuclear factor-κB (NF-κB) is a significant …

Human sirtuin regulators: the “success” stories

AM Curry, DS White, D Donu, Y Cen - Frontiers in Physiology, 2021 - frontiersin.org
The human sirtuins are a group of NAD+-dependent protein deacylases. They “erase” acyl
modifications from lysine residues in various cellular targets including histones, transcription …

Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19)

MR McCreary, PM Schnell, DA Rhoda - Scientific Reports, 2022 - nature.com
Resveratrol is a polyphenol that has been well studied and has demonstrated anti-viral and
anti-inflammatory properties that might mitigate the effects of COVID-19. Outpatients (N …

Impact of curcumin supplementation on expression of inflammatory transcription factors in hemodialysis patients: A pilot randomized, double-blind, controlled study

L Alvarenga, R Salarolli, LFMF Cardozo, RS Santos… - Clinical Nutrition, 2020 - Elsevier
Background & aims Chronic kidney disease (CKD) patients have numerous complications
associated with inflammation, which is a potential driver for cardiovascular disease …