[HTML][HTML] Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
[HTML][HTML] MicroRNA mimics or inhibitors as antiviral therapeutic approaches against COVID-19
C Hum, J Loiselle, N Ahmed, TA Shaw, C Toudic… - Drugs, 2021 - Springer
Coronaviruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
responsible for the coronavirus disease 2019 (COVID-19) pandemic, present a significant …
responsible for the coronavirus disease 2019 (COVID-19) pandemic, present a significant …
mirDIP 4.1—integrative database of human microRNA target predictions
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
[HTML][HTML] Nuclear outsourcing of RNA interference components to human mitochondria
S Bandiera, S Rüberg, M Girard, N Cagnard, S Hanein… - PloS one, 2011 - journals.plos.org
MicroRNAs (miRNAs) are small non-coding RNAs that associate with Argonaute proteins to
regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent …
regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent …
High-throughput analysis reveals miRNA upregulating α-2, 6-sialic acid through direct miRNA–mRNA interactions
F Jame-Chenarboo, HH Ng, D Macdonald… - ACS Central …, 2022 - ACS Publications
Chemical biology has revealed the importance of sialic acids as a major signal in physiology
and disease. The terminal modification α-2, 6-sialic acid is controlled by the enzymes …
and disease. The terminal modification α-2, 6-sialic acid is controlled by the enzymes …
[PDF][PDF] The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR‐21 function by directly targeting its precursor
MicroRNAs (miRNAs) play crucial roles in regulating gene expression in many cellular
contexts. Deregulation of miRNAs has been implicated in a number of disease conditions …
contexts. Deregulation of miRNAs has been implicated in a number of disease conditions …
A Lasso regression model for the construction of microRNA-target regulatory networks
Motivation: MicroRNAs have recently emerged as a major class of regulatory molecules
involved in a broad range of biological processes and complex diseases. Construction of …
involved in a broad range of biological processes and complex diseases. Construction of …
Web-based tools for miRNA studies analysis
F Shaker, A Nikravesh, R Arezumand… - Computers in biology …, 2020 - Elsevier
In recent years, thousands of microRNAs (miRNA) have been found in numerous species.
The huge data resulting from miRNA researches are ordered in several levels including …
The huge data resulting from miRNA researches are ordered in several levels including …
Joint analysis of miRNA and mRNA expression data
A Muniategui, J Pey, FJ Planes… - Briefings in …, 2013 - academic.oup.com
Abstract miRNAs are small RNA molecules (′ 22 nt) that interact with their target mRNAs
inhibiting translation or/and cleavaging the target mRNA. This interaction is guided by …
inhibiting translation or/and cleavaging the target mRNA. This interaction is guided by …
MicroRNA-24 is a novel regulator of aldosterone and cortisol production in the human adrenal cortex
S Robertson, SM MacKenzie, S Alvarez-Madrazo… - …, 2013 - Am Heart Assoc
Dysregulation of aldosterone or cortisol production can predispose to hypertension, as seen
in aldosterone-producing adenoma, a form of primary aldosteronism. We investigated the …
in aldosterone-producing adenoma, a form of primary aldosteronism. We investigated the …