Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Coronaviruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
responsible for the coronavirus disease 2019 (COVID-19) pandemic, present a significant …

MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …

MicroRNAs (miRNAs) are small non-coding RNAs that associate with Argonaute proteins to
regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent …

Chemical biology has revealed the importance of sialic acids as a major signal in physiology
and disease. The terminal modification α-2, 6-sialic acid is controlled by the enzymes …

MicroRNAs (miRNAs) play crucial roles in regulating gene expression in many cellular
contexts. Deregulation of miRNAs has been implicated in a number of disease conditions …

Motivation: MicroRNAs have recently emerged as a major class of regulatory molecules
involved in a broad range of biological processes and complex diseases. Construction of …

In recent years, thousands of microRNAs (miRNA) have been found in numerous species.
The huge data resulting from miRNA researches are ordered in several levels including …

Abstract miRNAs are small RNA molecules (′ 22 nt) that interact with their target mRNAs
inhibiting translation or/and cleavaging the target mRNA. This interaction is guided by …

Dysregulation of aldosterone or cortisol production can predispose to hypertension, as seen
in aldosterone-producing adenoma, a form of primary aldosteronism. We investigated the …