[HTML][HTML] ABC transporters affects tumor immune microenvironment to regulate cancer immunotherapy and multidrug resistance
Multidrug resistance (MDR) is the phenomenon in which cancer cells simultaneously
develop resistance to a broad spectrum of structurally and mechanistically unrelated drugs …
develop resistance to a broad spectrum of structurally and mechanistically unrelated drugs …
[HTML][HTML] Using the intranasal route to administer drugs to treat neurological and psychiatric illnesses: rationale, successes, and future needs
While the intranasal administration of drugs to the brain has been gaining both research
attention and regulatory success over the past several years, key fundamental and …
attention and regulatory success over the past several years, key fundamental and …
ATP-binding cassette transporters in reproduction: a new frontier
BACKGROUND The transmembrane ATP-binding cassette (ABC) transporters actively efflux
an array of clinically relevant compounds across biological barriers, and modulate …
an array of clinically relevant compounds across biological barriers, and modulate …
[HTML][HTML] The role of Staphylococcus aureus enterotoxin B in chronic rhinosinusitis with nasal polyposis
Z Chegini, M Didehdar, A Khoshbayan… - Cell Communication and …, 2022 - Springer
CRS with nasal polyps (CRSwNP) is a multifactorial disease, and various etiological factors
like bacterial superantigens are known to develop this disease. Recent studies reported that …
like bacterial superantigens are known to develop this disease. Recent studies reported that …
Implication of ABC transporters in non-proliferative diseases
TA Grigoreva, AV Sagaidak, DS Novikova… - European Journal of …, 2022 - Elsevier
ABC transporters play an essential role in the development of multidrug resistance and thus
are of interest in the context of anticancer therapy. However, MDR1, BCRP and MRP1 are …
are of interest in the context of anticancer therapy. However, MDR1, BCRP and MRP1 are …
Exosomes mediate interepithelial transfer of functional P‐glycoprotein in chronic rhinosinusitis with nasal polyps
Objective P‐glycoprotein (P‐gp) drives type‐2 helper T‐cell inflammation in chronic
rhinosinusitis with nasal polyps (CRSwNP) through unknown posttranslational mechanisms …
rhinosinusitis with nasal polyps (CRSwNP) through unknown posttranslational mechanisms …
[HTML][HTML] The role of exosomes in the pathophysiology of chronic rhinosinusitis
SK Mueller - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Non-invasive biomarker analysis has made repetitive and painless sampling over time
possible. Exosomes are being released from a parent cell and their cargo mirrors the cell …
possible. Exosomes are being released from a parent cell and their cargo mirrors the cell …
P‐glycoprotein is a marker of tissue eosinophilia and radiographic inflammation in chronic rhinosinusitis without nasal polyps
RE Feldman, AC Lam, PM Sadow… - International forum of …, 2013 - Wiley Online Library
Background P‐glycoprotein (P‐gp) is a membrane‐bound efflux pump that is upregulated in
chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and participates in epithelial …
chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and participates in epithelial …
P‐glycoprotein promotes epithelial T helper 2–associated cytokine secretion in chronic sinusitis with nasal polyps
Background Sinonasal epithelial cells are recognized as drivers of inflammation in chronic
sinusitis with nasal polyps (CRSwNP) through secretion of T helper 2 (Th2)‐promoting …
sinusitis with nasal polyps (CRSwNP) through secretion of T helper 2 (Th2)‐promoting …
[HTML][HTML] Emerging role of proteases in the pathogenesis of chronic rhinosinusitis with nasal polyps
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous upper airway
disease with multiple etiologies. Clinically, CRSwNP can be classified into either …
disease with multiple etiologies. Clinically, CRSwNP can be classified into either …