Immunology of Mycobacterium tuberculosis Infections
JK Sia, J Rengarajan - Microbiology spectrum, 2019 - Am Soc Microbiol
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
Mycobacterium tuberculosis infection of host cells in space and time
C Bussi, MG Gutierrez - FEMS microbiology reviews, 2019 - academic.oup.com
Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …
Evolution of Drug-Resistant Mycobacterium tuberculosis Strains and Their Adaptation to the Human Lung Environment
A Allué-Guardia, JI García, JB Torrelles - Frontiers in Microbiology, 2021 - frontiersin.org
In the last two decades, multi (MDR), extensively (XDR), extremely (XXDR) and total (TDR)
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …
Pathogenicity and virulence of Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …
The Macrophage: A Disputed Fortress in the Battle against Mycobacterium tuberculosis
CJ Queval, R Brosch, R Simeone - Frontiers in microbiology, 2017 - frontiersin.org
Mycobacterium tuberculosis (Mtb), the etiological agent of human tuberculosis (TB), has
plagued humans for thousands of years. TB still remains a major public health problem in …
plagued humans for thousands of years. TB still remains a major public health problem in …
Patterns, receptors, and signals: regulation of phagosome maturation
AM Pauwels, M Trost, R Beyaert, E Hoffmann - Trends in immunology, 2017 - cell.com
Recognition of microbial pathogens and dead cells and their phagocytic uptake by
specialized immune cells are essential to maintain host homeostasis. Phagosomes undergo …
specialized immune cells are essential to maintain host homeostasis. Phagosomes undergo …
[HTML][HTML] Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
MG Gutierrez, SS Master, SB Singh, GA Taylor… - Cell, 2004 - cell.com
Mycobacterium tuberculosis is an intracellular pathogen persisting within phagosomes
through interference with phagolysosome biogenesis. Here we show that stimulation of …
through interference with phagolysosome biogenesis. Here we show that stimulation of …
Antimicrobial mechanisms of phagocytes and bacterial evasion strategies
RS Flannagan, G Cosío, S Grinstein - Nature Reviews Microbiology, 2009 - nature.com
Professional phagocytes have a vast and sophisticated arsenal of microbicidal features.
They are capable of ingesting and destroying invading organisms, and can present …
They are capable of ingesting and destroying invading organisms, and can present …
Macrophages in tuberculosis: friend or foe
E Guirado, LS Schlesinger, G Kaplan - Seminars in immunopathology, 2013 - Springer
Tuberculosis (TB) remains one of the greatest threats to human health. The causative
bacterium, Mycobacterium tuberculosis (Mtb), is acquired by the respiratory route. It is …
bacterium, Mycobacterium tuberculosis (Mtb), is acquired by the respiratory route. It is …
The emerging field of lipidomics
MR Wenk - Nature reviews Drug discovery, 2005 - nature.com
The crucial role of lipids in cell, tissue and organ physiology is demonstrated by a large
number of genetic studies and by many human diseases that involve the disruption of lipid …
number of genetic studies and by many human diseases that involve the disruption of lipid …