Mesenchymal stem cells (MSCs) have regenerative, immunoregulatory properties and can
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …

For several decades, multipotent mesenchymal stromal cells (MSCs) have been extensively
studied for their therapeutic potential across a wide range of diseases. In the preclinical …

Background Senescent cells, which can release factors that cause inflammation and
dysfunction, the senescence-associated secretory phenotype (SASP), accumulate with …

Apoptosis is critical for maintaining bodily homeostasis and produces a large number of
apoptotic extracellular vesicles (apoEVs). Several types of cancer cells display reduced …

Novel therapies are urgently needed to address the rising incidence and prevalence of
acute kidney injury (AKI) and chronic kidney disease (CKD). Mesenchymal stem/stromal …

Due to their robust immunomodulatory capabilities, mesenchymal stem/stromal cells (MSCs)
have been used as a cellular therapy for a number of human diseases. Part of the …

Background Chronic inflammatory conditions like obesity may adversely impact the
biological functions underlying the regenerative potential of mesenchymal stromal/stem cells …

Severe cases of COVID-19 infection, often leading to death, have been associated with
variants of acute respiratory distress syndrome (ARDS). Cell therapy with mesenchymal …

Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus
emphasizing the need to better understand the molecular mechanisms of damage and …

Psoriasis is a common, chronic immune-mediated systemic disease that had no effective
and durable treatment. Mesenchymal stem cells (MSCs) have immunomodulatory …