After an ischemic injury, the heart undergoes a complex process of structural and functional
remodeling that involves several steps, including inflammatory and fibrotic responses. In this …

Systemic sclerosis (SSc) is a disease of connective tissue with high rate of morbidity and
mortality highlighted by extreme fibrosis affecting various organs such as the dermis, lungs …

The influence of son of sevenless homolog 1 (SOS1) on invasion and metastasis of
hepatocellular carcinoma (HCC) cells was investigated. HCC cells were transfected with …

Many different regulatory mechanisms of renal fibrosis are known to date, and those related
to transforming growth factor-β1 (TGF-β1)-induced signaling have been studied in greater …

Hereditary gingival fibromatosis (HGF) is a rare inherited condition with fibromatoid
hyperplasia of the gingival tissue that exhibits great genetic heterogeneity. Five distinct loci …

Abstract The Son of Sevenless 1 (SOS1) guanine nucleotide exchange factor, prevalent
across eukaryotic species, plays a pivotal role in facilitating the attachment of RAS protein to …

Pharmacogenomic analysis based on drug transcriptome characteristics is widely used to
identify mechanisms of action. The purpose of this study was to elucidate the molecular …

Background: Previous reports showed that mouse embryonic fibroblasts (MEFs) could
support pluripotent stem cell self-renewal and maintain their pluripotency. The goal of this …

罗业浩1 ,陈秋霞1 ,吕挺2 ,区佩琪1 ,曹知勇2 ,段雪琳 Page 1 6$ 外泌体在肝纤维化发生发展及
诊治中的作用 罗业浩1 ,陈秋霞1 ,吕挺2 ,区佩琪1 ,曹知勇2 ,段雪琳1 1 广西中医药大学,壮医方药 …

An increasing number of studies have demonstrated that exosomes are closely associated
with liver fibrosis and mediate the process of liver fibrosis by participating in cytokine …