Liquid biopsies: Potential and challenges
I Heidrich, L Ačkar… - … Journal of Cancer, 2021 - Wiley Online Library
The analysis of tumor cells or tumor cell products obtained from blood or other body fluids
(“liquid biopsy”[LB]) provides a broad range of opportunities in the field of oncology. Clinical …
(“liquid biopsy”[LB]) provides a broad range of opportunities in the field of oncology. Clinical …
Bridging biological cfDNA features and machine learning approaches
T Moser, S Kühberger, I Lazzeri, G Vlachos, E Heitzer - Trends in Genetics, 2023 - cell.com
Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to
revolutionize precision oncology and blood-based cancer screening. Recent technological …
revolutionize precision oncology and blood-based cancer screening. Recent technological …
Non-invasive biomarkers for early detection of breast cancer
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …
survival from the disease. The mammogram is widely used for early detection of breast …
RNA methylations in human cancers
RNA methylations, as the prevalent post-transcriptional modifications, are critical in
regulating various biological processes, such as RNA transcription, splicing, structure …
regulating various biological processes, such as RNA transcription, splicing, structure …
DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …
population-based cancer screening methods remain an unmet need, since cancer detection …
Cell-free DNA: hope and potential application in cancer
Y Yan, Q Guo, F Wang, R Adhikari, Z Zhu… - Frontiers in cell and …, 2021 - frontiersin.org
Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as
biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA …
biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA …
Breast cancer, screening and diagnostic tools: All you need to know
D Barba, A León-Sosa, P Lugo, D Suquillo… - Critical reviews in …, 2021 - Elsevier
Breast cancer is one of the most frequent malignancies among women worldwide. Methods
for screening and diagnosis allow health care professionals to provide personalized …
for screening and diagnosis allow health care professionals to provide personalized …
Perspectives on liquid biopsy for label‐free detection of “circulating tumor cells” through intelligent lab‐on‐chips
Circulating tumor cells (CTCs) are rare tumor cells released from primary, metastatic, or
recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral …
recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral …
[HTML][HTML] Circulating biomarkers in breast cancer
KN Seale, KHR Tkaczuk - Clinical breast cancer, 2022 - Elsevier
Breast cancer management has progressed immensely over the decades, but the disease is
still a major source of morbidity and mortality worldwide. Even with enhanced imaging …
still a major source of morbidity and mortality worldwide. Even with enhanced imaging …
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook
E Lianidou - Molecular Oncology, 2021 - Wiley Online Library
Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …