Acute respiratory distress syndrome (ARDS) caused by SARS-CoV-2 is largely the result of
a dysregulated host response, followed by damage to alveolar cells and lung fibrosis …

Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional
overdose of acetaminophen (APAP) has affected patients for decades, and involves the …

Afterglow luminescence (long persistent luminescence) holds great potential for
nonbackground molecular imaging. However, current afterglow probes are mainly …

The gut microbiota drives individual sensitivity to excess acetaminophen (APAP)-mediated
hepatotoxicity. It has been reported that the bacterium Akkermansia muciniphila protects …

Acetaminophen (APAP) is one of the most popular and safe pain medications worldwide.
However, due to its wide availability, it is frequently implicated in intentional or unintentional …

Idiosyncratic drug-induced liver injury (IDILI) is a rare but potentially severe adverse drug
reaction that should be considered in patients who develop laboratory criteria for liver injury …

The mitochondrion is an organelle that plays a vital role in the regulation of hepatic cellular
redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both …

The data-independent acquisition (DIA) approach has recently been introduced as a novel
mass spectrometric method that promises to combine the high content aspect of shotgun …

Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress.
However, its source, pathophysiological role and possible therapeutic potential if targeted …

The transport of specific molecules across lipid membranes is an essential function of all
living organisms. The processes are usually mediated by specific transporters. One of the …