Hypocalcemia in COVID-19: Prevalence, clinical significance and therapeutic implications

L di Filippo, M Doga, S Frara, A Giustina - Reviews in Endocrine and …, 2022 - Springer
COVID-19 extra-pulmonary features include several endocrine manifestations and these are
becoming strongly clinically relevant in patients affected influencing disease severity and …

Pathogenesis and mechanisms of SARS-CoV-2 infection in the intestine, liver, and pancreas

Z Khreefa, MT Barbier, AR Koksal, G Love, L Del Valle - Cells, 2023 - mdpi.com
The novel coronavirus, SARS-CoV-2, rapidly spread worldwide, causing an ongoing global
pandemic. While the respiratory system is the most common site of infection, a significant …

Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Intravenous BCG vaccination reduces SARS-CoV-2 severity and promotes extensive reprogramming of lung immune cells

AK Singh, R Wang, KA Lombardo, M Praharaj… - Iscience, 2023 - cell.com
Summary Bacillus Calmette-Guérin (BCG) confers heterologous immune protection against
viral infections and has been proposed as vaccine against SARS-CoV-2 (SCV2). Here, we …

Myeloid-derived suppressor cells as a potential biomarker and therapeutic target in COVID-19

M Rowlands, F Segal, D Hartl - Frontiers in immunology, 2021 - frontiersin.org
Clinical presentations of COVID-19 are highly variable, yet the precise mechanisms that
govern the pathophysiology of different disease courses remain poorly defined. Across the …

[HTML][HTML] Friend or Foe? Implication of the autophagy-lysosome pathway in SARS-CoV-2 infection and COVID-19

W He, Y Gao, J Zhou, Y Shi, D Xia… - International Journal of …, 2022 - ncbi.nlm.nih.gov
There is increasing amount of evidence indicating the close interplays between the
replication cycle of SARS-CoV-2 and the autophagy-lysosome pathway in the host cells …

[HTML][HTML] Role of myeloid-derived suppressor cells in viral respiratory infections; Hints for discovering therapeutic targets for COVID-19

K Koushki, M Salemi, SM Miri, Y Arjeini… - Biomedicine & …, 2021 - Elsevier
The expansion of myeloid-derived suppressor cells (MDSCs), known as heterogeneous
population of immature myeloid cells, is enhanced during several pathological conditions …

Mild and asymptomatic COVID-19 convalescents present long-term endotype of immunosuppression associated with neutrophil subsets possessing regulatory …

I Siemińska, K Węglarczyk, M Surmiak… - Frontiers in …, 2021 - frontiersin.org
The SARS-CoV-2 infection [coronavirus disease 2019 (COVID-19)] is associated with
severe lymphopenia and impaired immune response, including expansion of myeloid cells …

Perspective of HLA-G induced immunosuppression in SARS-CoV-2 infection

A Lin, WH Yan - Frontiers in immunology, 2021 - frontiersin.org
COVID-19, the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), has threatened public health worldwide. Host antiviral immune responses are …

Myeloid-derived suppressor cells in COVID-19: the paradox of good

G Grassi, S Notari, S Gili, V Bordoni, R Casetti… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Viral replication in the …