Fibroblasts are the major cell population of connective tissue, including the skin dermis, and
are best known for their function in depositing and remodelling the extracellular matrix …

Keloids, a pathological scar that is induced by the consequence of aberrant wound healing,
is still a major global health concern for its unsatisfactory treatment outcomes. HIF-1α, a …

Idiopathic subglottic stenosis (ISGS) is a rare fibrotic disease of the upper trachea with an
unknown pathomechanism. It typically affects adult Caucasian female patients, leading to …

Introduction Keloids form as a pathological response to skin wound healing, and their
etiopathology is poorly understood. Myofibroblasts, which are cells transformed from normal …

Objective: Anoikis, a kind of programmed cell death that is triggered when cells lose contact
with each other or with the matrix. However, the potential value of anoikis-related genes …

Objectives Keloid is a highly aggressive fibrotic disease resulting from excessive
extracellular matrix deposition after dermal injury. Intra-lesional injection of triamcinolone …

With the development of single-cell sequencing technology, the cellular composition of more
and more tissues is being elucidated. As the whole nervous system has been extensively …

Purpose: The pathophysiology of keloid remains unclear. Exploring the immune
heterogeneity and new biomarkers of keloids can help design new therapeutic targets for …

Schwann cells (SCs), a type of glial cell in the peripheral nervous system, can serve as a
source of mesenchymal stem cells (MSCs) to repair injured pulp. This study aimed to …

Abstract The IncRNA Malat1 was initially believed to be dispensable for physiology due to
the lack of observable phenotypes in Malat1 knockout (KO) mice. However, our study …