The red flour beetle T. castaneum: elaborate genetic toolkit and unbiased large scale RNAi screening to study insect biology and evolution

M Klingler, G Bucher - EvoDevo, 2022 - Springer
The red flour beetle Tribolium castaneum has emerged as an important insect model system
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …

Gene expression mapping of the neuroectoderm across phyla–conservation and divergence of early brain anlagen between insects and vertebrates

N Posnien, VS Hunnekuhl, G Bucher - Elife, 2023 - elifesciences.org
Gene expression has been employed for homologizing body regions across bilateria. The
molecular comparison of vertebrate and fly brains has led to a number of disputed homology …

The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology

C Schmitt-Engel, D Schultheis, J Schwirz… - Nature …, 2015 - nature.com
Genetic screens are powerful tools to identify the genes required for a given biological
process. However, for technical reasons, comprehensive screens have been restricted to …

Screens in fly and beetle reveal vastly divergent gene sets required for developmental processes

MS Hakeemi, S Ansari, M Teuscher, M Weißkopf… - BMC biology, 2022 - Springer
Background Most of the known genes required for developmental processes have been
identified by genetic screens in a few well-studied model organisms, which have been …

Non-invasive long-term fluorescence live imaging of Tribolium castaneum embryos

F Strobl, EHK Stelzer - Development, 2014 - journals.biologists.com
Insect development has contributed significantly to our understanding of metazoan
development. However, most information has been obtained by analyzing a single species …

Wnt/β-catenin signaling integrates patterning and metabolism of the insect growth zone

G Oberhofer, D Grossmann, JL Siemanowski… - …, 2014 - journals.biologists.com
Wnt/β-catenin and hedgehog (Hh) signaling are essential for transmitting signals across cell
membranes in animal embryos. Early patterning of the principal insect model, Drosophila …

Antifeedant Activities of Lignans from Stem Bark of Zanthoxylum armatum DC. against Tribolium castaneum

W Zhang, Y Wang, Z Geng, S Guo, J Cao, Z Zhang… - Molecules, 2018 - mdpi.com
The speciation of a methanolic extract of Zanthoxylum armatum stem bark has enabled the
isolation and characterization of 11 known lignans. Among them, five compounds (6, 8–11) …

A timer gene network is spatially regulated by the terminal system in the Drosophila embryo

E Clark, M Battistara, MA Benton - Elife, 2022 - elifesciences.org
In insect embryos, anteroposterior patterning is coordinated by the sequential expression of
the 'timer'genes caudal, Dichaete, and odd-paired, whose expression dynamics correlate …

[HTML][HTML] An anterior medial cell population with an apical-organ-like transcriptional profile that pioneers the central nervous system in the centipede Strigamia maritima

VS Hunnekuhl, M Akam - Developmental biology, 2014 - Elsevier
The apical plate of primary marine larvae is characterized by a common set of transcription
factors comprising six3, rx, hbn, nk2. 1 and FoxQ2. It harbours the apical organ, a neural and …

[HTML][HTML] Canonical terminal patterning is an evolutionary novelty

EJ Duncan, MA Benton, PK Dearden - Developmental biology, 2013 - Elsevier
Patterning of the terminal regions of the Drosophila embryo is achieved by an exquisitely
regulated signal that passes between the follicle cells of the ovary, and the developing …