Fluoride contamination, health problems and remediation methods in Asian groundwater: A comprehensive review
Highlights•The status of fluoride contamination in groundwater of Asian countries is
reviewed.•India, Pakistan and China are critically affected by fluoride contamination.•Dental …
reviewed.•India, Pakistan and China are critically affected by fluoride contamination.•Dental …
Molecular mechanisms of fluoride toxicity
Halfway through the twentieth century, fluoride piqued the interest of toxicologists due to its
deleterious effects at high concentrations in human populations suffering from fluorosis and …
deleterious effects at high concentrations in human populations suffering from fluorosis and …
Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach
JV Castell, MT Donato, MJ Gómez-Lechón - Experimental and Toxicologic …, 2005 - Elsevier
Lung is a target organ for the toxicity of inhalated compounds. The respiratory tract is
frequently exposed to elevated concentrations of these compounds and become the primary …
frequently exposed to elevated concentrations of these compounds and become the primary …
Molecular mechanisms of cytotoxicity and apoptosis induced by inorganic fluoride
NI Agalakova, GP Gusev - International Scholarly Research …, 2012 - Wiley Online Library
Fluoride (F) is ubiquitous natural substance and widespread industrial pollutant. Although
low fluoride concentrations are beneficial for normal tooth and bone development, acute or …
low fluoride concentrations are beneficial for normal tooth and bone development, acute or …
Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation
K Kubota, DH Lee, M Tsuchiya, CS Young… - Journal of Biological …, 2005 - ASBMB
The mechanism of how fluoride causes fluorosis remains unknown. Exposure to fluoride can
inhibit protein synthesis, and this may also occur by agents that cause endoplasmic …
inhibit protein synthesis, and this may also occur by agents that cause endoplasmic …
Effects of fluoride on the expression of NCAM, oxidative stress, and apoptosis in primary cultured hippocampal neurons
M Zhang, A Wang, W He, P He, B Xu, T Xia, X Chen… - Toxicology, 2007 - Elsevier
The mechanisms underlying the neurotoxicity of endemic fluorosis still remain unknown. To
investigate the expression level of neural cell adhesion molecules (NCAM), oxidative stress …
investigate the expression level of neural cell adhesion molecules (NCAM), oxidative stress …
Involvement of both mitochondrial-and death receptor-dependent apoptotic pathways regulated by Bcl-2 family in sodium fluoride-induced apoptosis of the human …
JH Lee, JY Jung, YJ Jeong, JH Park, KH Yang… - Toxicology, 2008 - Elsevier
Sodium fluoride (NaF) has been shown to be cytotoxic and produces inflammatory
responses in humans. However, the cellular mechanisms underlying the NaF-induced …
responses in humans. However, the cellular mechanisms underlying the NaF-induced …
[HTML][HTML] DNA damage, apoptosis and cell cycle changes induced by fluoride in rat oral mucosal cells and hepatocytes
LF He, JG Chen - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
AIM: To study the effect of fluoride on oxidative stress, DNA damage and apoptosis as well
as cell cycle of rat oral mucosal cells and hepatocytes. METHODS: Ten male SD rats …
as cell cycle of rat oral mucosal cells and hepatocytes. METHODS: Ten male SD rats …
Fluorescent probe for detection of fluoride in water and bioimaging in A549 human lung carcinoma cells
Fluorescent probe for detection of fluoride in water and bioimaging in A549 human lung
carcinoma cells - Chemical Communications (RSC Publishing) DOI:10.1039/B908745A Royal …
carcinoma cells - Chemical Communications (RSC Publishing) DOI:10.1039/B908745A Royal …
Antioxidant phytochemicals for the prevention of fluoride-induced oxidative stress and apoptosis: A review
Fluorosis is a major public health problem globally. The non-availability of specific treatment
and the irreversible nature of dental and skeletal lesions poses a challenge in the …
and the irreversible nature of dental and skeletal lesions poses a challenge in the …