The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

The molecular imaging of apoptosis remains an important method for the diagnosis and
monitoring of the progression of certain diseases and the evaluation of the efficacy of …

Apoptosis, with a hallmark of upregulated protease Caspase-3, has been frequently imaged
with various probes to reveal the therapeutic efficiencies of different drugs. However …

Stimuli-responsive in situ self-assembly of small molecule probes into nanostructures has
been promising for the construction of molecular probes for in vivo imaging. In the past few …

Abstract Objective Excess molybdenum (Mo) is harmful to the body, and the kidney is the
vital target organ for Mo exposure. This study focused on the impacts of excess Mo on …

Purpose: Positron emission tomography (PET) imaging of apoptosis is very important for
early evaluation of tumor therapeutic efficacy. A stimuli-responsive probe based on the …

Background: Hepatocellular carcinoma (HCC) is the main type of primary liver cancer and
shows a heavy burden worldwide. Its recurrence and mortality rate are still uncontrolled by …

Controlling the access of proteases to cleavable peptides placed at specific locations within
macromolecular architectures represents a powerful strategy for biologically responsive …

To date, a wide variety of potential PET-apoptosis imaging radiopharmaceuticals targeting
apoptosis-induced cell membrane asymmetry and acidification, as well as caspase 3 …

Apoptosis is a feature of stroke and Alzheimer's disease (AD), yet there is no accepted
method to detect or follow apoptosis in the brain in vivo. We developed a bifunctional tracer …