Life emerges from thousands of biochemical processes occurring within a shared
intracellular environment. We have gained deep insights from in vitro reconstitution of …

Zinc is an essential micronutrient, and its deficiency is perhaps the most prevalent and least
understood worldwide. Recent advances have expanded the understanding of zinc's unique …

Phase separation is a ubiquitous and emerging mechanism underlying intracellular
organization. Yet how distinct molecular compositions in phase-separated condensates are …

While fundamentally important, the intracellular diffusion of small (≲ 1 kDa) solutes has been
difficult to elucidate due to challenges in both labeling and measurement. Here we quantify …

A new theoretical framework that enables the use of differential dynamic microscopy (DDM)
in fluorescence imaging mode to quantify in situ protein adsorption onto nanoparticles (NP) …

Exerting forces on biomolecules inside living cells would allow us to probe their dynamic
interactions in their native environment. Magnetic iron oxide nanoparticles represent a …

Cellular functions are regulated with high spatial control through the local activation of
chemical processes in a complex inhomogeneous matrix. The development of synthetic …

Diffusive motion accompanies many physical and biological processes. The Stokes–
Sutherland–Einstein relation for the translational diffusion coefficient, DT, agrees with …

Purpose Recent interest in understanding effects of high dose-rate ('FLASH') radiobiology
has prompted a number of groups to model the chemical reactions that might be involved …

Holotomography, a three-dimensional quantitative phase imaging technique, presents an
innovative, noninvasive approach to studying biological samples by exploiting the refractive …