Potential diagnostic consequences of applying non‐invasive prenatal testing: population‐based study from a country with existing first‐trimester screening
Objectives Targeted non‐invasive prenatal testing (NIPT) tests for trisomies 21, 18 and 13
and sex chromosome aneuploidies and could be an alternative to traditional karyotyping …
and sex chromosome aneuploidies and could be an alternative to traditional karyotyping …
High-throughput massively parallel sequencing for fetal aneuploidy detection from maternal plasma
TJ Jensen, T Zwiefelhofer, RC Tim, Ž Džakula, SK Kim… - PloS one, 2013 - journals.plos.org
Background Circulating cell-free (ccf) fetal DNA comprises 3–20% of all the cell-free DNA
present in maternal plasma. Numerous research and clinical studies have described the …
present in maternal plasma. Numerous research and clinical studies have described the …
Noninvasive prenatal testing for trisomy 21: Challenges for implementation in A ustralia
L Hui, J Hyett - Australian and New Zealand Journal of …, 2013 - Wiley Online Library
The term 'Non invasive prenatal testing'is used to describe the rapidly emerging molecular
technologies related to cell free DNA assessment that are being applied to prenatal …
technologies related to cell free DNA assessment that are being applied to prenatal …
The epigenome view: An effort towards non-invasive prenatal diagnosis
EA Papageorgiou, G Koumbaris, E Kypri… - Genes, 2014 - mdpi.com
Epigenetic modifications have proven to play a significant role in cancer development, as
well as fetal development. Taking advantage of the knowledge acquired during the last …
well as fetal development. Taking advantage of the knowledge acquired during the last …
Methods and compositions for noninvasive prenatal diagnosis of fetal aneuploidies
PC Patsalis, EA Papageorgiou - US Patent 9,249,462, 2016 - Google Patents
FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …
Modified methylated DNA immunoprecipitation protocol for noninvasive prenatal diagnosis of Down syndrome
Aim Methylated DNA immunoprecipitation real‐time quantitative polymerase chain reaction
(MeDIP‐real‐time qPCR) has been introduced as noninvasive prenatal test that has shown …
(MeDIP‐real‐time qPCR) has been introduced as noninvasive prenatal test that has shown …
qRT-PCR evaluation of the transcriptional response of zebra mussel to heavy metals
Background The transcriptional response of adult zebra mussels (Dreissena polymorpha) to
heavy metals (mercury, copper, and cadmium) was analyzed by quantitative Real-Time …
heavy metals (mercury, copper, and cadmium) was analyzed by quantitative Real-Time …
Maternal plasma sequencing: a powerful tool towards fetal whole genome recovery
EA Papageorgiou, PC Patsalis - BMC medicine, 2013 - Springer
Noninvasive prenatal diagnosis of chromosomal aneuploidies, although challenging, has
been achieved through the implementation of novel methodologies such as methylated DNA …
been achieved through the implementation of novel methodologies such as methylated DNA …
The diagnosis pattern of mid-trimester fetal chromosomal aneuploidy in Xuzhou and the clinical applications
Y Fang, G Wang, C Wang, F Suo, M Gu… - Cell biochemistry and …, 2015 - Springer
The objective of this study is to explore the diagnosis pattern of mid-trimester fetal
chromosomal aneuploidy and its clinical applications. A large group of pregnant women (18 …
chromosomal aneuploidy and its clinical applications. A large group of pregnant women (18 …
Multiplexed parallel analysis of targeted genomic regions for non-invasive prenatal testing
G Koumbaris, E Kypri, K Tsangaras… - US Patent …, 2021 - Google Patents
The invention provides methods for non-invasive prenatal testing that allow for detecting risk
of chromosomal and subchromosomal abnormalities, including but not limited to …
of chromosomal and subchromosomal abnormalities, including but not limited to …