Risk factors for endemic chronic kidney disease of unknown etiology in Sri Lanka: Retrospect of water security in the dry zone

O Hettithanthri, S Sandanayake… - Science of the Total …, 2021 - Elsevier
The prevalence of chronic kidney disease of unknown etiology (CKDu) is receiving
considerable attention due to the serious threat to human health throughout the world …

Groundwater as a potential cause of Chronic Kidney Disease of unknown etiology (CKDu) in Sri Lanka: a review

S Imbulana, K Oguma - Journal of Water and Health, 2021 - iwaponline.com
Abstract The cause of Chronic Kidney Disease of unknown etiology (CKDu) in the rural dry
zone of Sri Lanka remains unidentified, despite vast research efforts that brought about an …

Inhaled silica nanoparticles cause chronic kidney disease in rats

F Sasai, KL Rogers, DJ Orlicky… - American Journal …, 2022 - journals.physiology.org
Silica nanoparticles (SiNPs) released during the burning of sugarcane have been
postulated to have a role in chronic kidney disease of unknown etiology. We tested the …

Intranasal administration of sugarcane ash causes chronic kidney disease in rats

CA Roncal-Jimenez, KL Rogers… - American Journal …, 2024 - journals.physiology.org
Silica nanoparticles found in sugarcane ash have been postulated to be a toxicant
contributing to chronic kidney disease (CKD) of unknown etiology. However, although the …

Sugarcane ash and sugarcane ash-derived silica nanoparticles alter cellular metabolism in human proximal tubular kidney cells

AD Stem, KL Rogers, JR Roede… - Environmental …, 2023 - Elsevier
Multiple epidemics of chronic kidney disease of an unknown etiology (CKDu) have emerged
in agricultural communities around the world. Many factors have been posited as potential …

Hydrogeochemical factors controlling the occurrence of chronic kidney disease of unknown etiology (CKDu)

Q Shi, Z Gao, H Guo, X Zeng, S Sandanayake… - Environmental …, 2023 - Springer
Chronic kidney disease of unknown etiology (CKDu) has posed a serious threat to human
health around the world. The link between the prevalence of CKDu and groundwater …

Natural and anthropogenic controls of groundwater quality in sri lanka: Implications for chronic kidney disease of unknown etiology (ckdu)

S Xu, SL Li, F Yue, C Udeshani, R Chandrajith - Water, 2021 - mdpi.com
Poor groundwater quality in household wells is hypothesized as being a potential
contributor to chronic kidney disease of unknown etiology (CKDu) in Sri Lanka. However …

Silica nanoparticles and Mesoamerican nephropathy: a case series

KL Rogers, CA Roncal-Jimenez, R Leiva… - American Journal of …, 2024 - ajkd.org
Silica exposure has been associated with chronic kidney disease of unknown etiology
(CKDu). 1-4 Both sugarcane and rice contain amorphous silica nanoparticles (SiNPs) that …

[HTML][HTML] Geochemistry of groundwater in the semi-arid crystalline terrain of Sri Lanka and its health implications among agricultural communities

WA Udeshani, NH Koralegedara, SK Gunatilake, SL Li… - Water, 2022 - mdpi.com
Chronic kidney disease with uncertain etiology (CKDu) is an emerging health problem in Sri
Lanka, particularly among the dry-zone farming communities that use groundwater for …

Major and trace elements in human kidney stones: a preliminary investigation in Beijing, China

Y Tian, G Han, R Qu, C Xiao - Minerals, 2022 - mdpi.com
Kidney stone disease affects people globally, with its prevalence on the rise. Given the
importance of elements' function in formation of kidney stones, this study investigated major …