Clostridioides (formerly Clostridium) difficile is the most important infectious cause of
antibiotic-associated diarrhea worldwide and a leading cause of healthcare-associated …

Clostridium (Clostridioides) difficile is a gram-positive, spore-forming bacterium that is an
important cause of disease in people, a variably important cause of disease in some animal …

Importance Proton pump inhibitor (PPI) use may lead to infections through alteration of the
microbiota or direct action on the immune system. However, only a few studies were …

Proton pump inhibitors (PPIs) are among the most prescribed drugs worldwide and include
omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole. Their use in …

Gut microbiota composition during the first years of life is variable, dynamic and influenced
by both prenatal and postnatal factors, such as maternal antibiotics administered during …

There has been an increase in the prevalence of Clostridioides difficile (C. diff) causing
significant economic impact on the health care system. Although toxigenic C. diff carriage is …

Background Clostridioides difficile is considered an urgent threat to human health by the US
Centers for Disease Control and Prevention. In recent years, C. difficile has been reported …

Proton pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA) are commonly
used medications in neonates and infants for the treatment of gastroesophageal reflux …

Proton pump inhibitors (PPIs) have been available for over three decades and are among
the most commonly prescribed medications. They are effective in treating a variety of gastric …

Objectives To compare the incidence, epidemiology, testing patterns, treatment, and
outcomes of Clostridioides difficile infection (CDI) among hospitalized pediatric patients from …