Homeobox (HOX) transcription factors, encoded by a subset of homeodomain superfamily
genes, play pivotal roles in many aspects of cellular physiology, embryonic development …

HOX genes are commonly known for their role in embryonic development, defining the
positional identity of most structures along the anterior–posterior axis. In postembryonic life …

Abstract Background Prostate cancer (PCa) remains the second leading cause of deaths
due to cancer in the United States in men. The aim of this study was to perform an integrative …

Objectives Investigate the DNA copy number and the methylation profile of the homeobox
genes HOXA5, HOXA7, HOXA9, HOXB5, HOXB13, HOXC12, HOXC13, HOXD10, HOXD11 …

Background Aberrant DNA methylation plays an crucial role in tumorigenesis through
regulating gene expression. Nevertheless, the exact role of methylation in the …

Well differentiated liposarcoma (WD‐LPS) is a relatively rare tumour, with fewer than 50
cases occurring per year in the UK. These tumours are both chemotherapy‐and …

Epigenetic marks, such as DNA methylation and histone-tail modifications, as well as
noncoding RNAs, are gathering increasing interest as possible diagnostic or prognostic …

Increasing evidence reveals that epigenetic biomarkers, mainly markers of DNA methylation
or noncoding RNA molecules, can become valuable tools as minimally invasive diagnostic …

Introdução: Os cancros do pulmão (CaPl), próstata (CaP) e coloretal (CaCr) são os três mais
incidentes no sexo masculino a nível mundial. Apesar dos avanços científicos, a procura de …

Epidemiological studies indicate a reduced risk and a lower incidence of hormone-
dependent cancer types in populations following a traditional Asian diet rich in …