Immunoglobulin A (IgA) plays a key role in defending mucosal surfaces against attack by
infectious microorganisms. Such sites present a major site of susceptibility due to their vast …

This article reviews technology trends in antibody purification. Section 1 discusses non-
chromatography methods, including precipitation, liquid–liquid extraction, and high …

Immunoglobulin A (IgA) is commonly recognized as the most prevalent antibody (Ab) at
mucosal sites with an important role in defense by shielding mucosal surfaces from invasion …

Immunoglobulin A (IgA) is the most prevalent antibody at mucosal sites, and has an
important role in defense by preventing invasion of pathogens. Traditionally, IgA has been …

Background Single-domain antibody fragments possess structural features, such as a small
dimension, an elevated stability, and the singularity of recognizing epitopes non-accessible …

Immunoglobulin A (IgA) is the most abundantly produced antibody isotype in mammals. The
primary function of IgA is to maintain homeostasis at mucosal surfaces and play a role in …

In the past three decades, a great interest has arisen in the use of immunoglobulins as
therapeutic agents. In particular, since the approval of the first monoclonal antibody …

The use of monoclonal antibodies (mAbs) has become a mainstream strategy for the
treatment of cancer. After binding to the target antigen, they mediate a plethora of effector …

Currently all approved anti‐cancer therapeutic monoclonal antibodies (mAbs) are of the IgG
isotype, which rely on Fcgamma receptors (FcγRs) to recruit cellular effector functions. In …

Monoclonal antibodies (mAbs) have become an important addition to chemo-and/or
radiotherapy for the treatment of cancer. They have multiple effector functions that can lead …