International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors
C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
Hydrogen sulfide and cell signaling
L Li, P Rose, PK Moore - Annual review of pharmacology and …, 2011 - annualreviews.org
Hydrogen sulfide (H2S) is a gaseous mediator synthesized from cysteine by cystathionine γ
lyase (CSE) and other naturally occurring enzymes. Pharmacological experiments using …
lyase (CSE) and other naturally occurring enzymes. Pharmacological experiments using …
Regulation of autophagy of the heart in ischemia and reperfusion
SV Popov, AV Mukhomedzyanov, NS Voronkov… - Apoptosis, 2023 - Springer
Abstract Ischemia/reperfusion (I/R) of the heart leads to increased autophagic flux.
Preconditioning stimulates autophagic flux by AMPK and PI3-kinase activation and mTOR …
Preconditioning stimulates autophagic flux by AMPK and PI3-kinase activation and mTOR …
Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis
DJ Polhemus, K Kondo, S Bhushan, SC Bir… - Circulation: Heart …, 2013 - Am Heart Assoc
Background—Hydrogen sulfide (H2S) has been shown to induce angiogenesis in in vitro
models and to promote vessel growth in the setting of hindlimb ischemia. The goal of the …
models and to promote vessel growth in the setting of hindlimb ischemia. The goal of the …
Hydrogen sulfide and autophagy: a double edged sword
D Wu, H Wang, T Teng, S Duan, A Ji, Y Li - Pharmacological research, 2018 - Elsevier
Hydrogen sulfide (H 2 S) has been considered the third gaseous signaling molecule that
plays important roles in a wide range of physiological and pathological conditions. However …
plays important roles in a wide range of physiological and pathological conditions. However …
Autophagy as a therapeutic target for ischaemia/reperfusion injury? Concepts, controversies, and challenges
K Przyklenk, Y Dong, VV Undyala… - Cardiovascular …, 2012 - academic.oup.com
Autophagy is the tightly orchestrated cellular 'housekeeping'process responsible for the
degradation and disposal of damaged and dysfunctional organelles and protein aggregates …
degradation and disposal of damaged and dysfunctional organelles and protein aggregates …
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects
Emerging work demonstrates the dual regulation of mitochondrial function by hydrogen
sulfide (H2S), including, at lower concentrations, a stimulatory effect as an electron donor …
sulfide (H2S), including, at lower concentrations, a stimulatory effect as an electron donor …
Hydrogen sulfide-mediated cardioprotection: mechanisms and therapeutic potential
H2S (hydrogen sulfide), viewed with dread for more than 300 years, is rapidly becoming a
ubiquitously present and physiologically relevant signalling molecule. Knowledge of the …
ubiquitously present and physiologically relevant signalling molecule. Knowledge of the …
Cardioprotective effects of hydrogen sulfide
The gaseous mediator hydrogen sulfide (H2S) is synthesized mainly by cystathionine γ-
lyase in the heart and plays a role in the regulation of cardiovascular homeostasis. Here we …
lyase in the heart and plays a role in the regulation of cardiovascular homeostasis. Here we …
Autophagy: definition, molecular machinery, and potential role in myocardial ischemia-reperfusion injury
Y Dong, VV Undyala, RA Gottlieb… - Journal of …, 2010 - journals.sagepub.com
Autophagy is the endogenous, tightly regulated cellular" housekeeping" process
responsible for the degradation of damaged and dysfunctional cellular organelles and …
responsible for the degradation of damaged and dysfunctional cellular organelles and …