Neuroendocrine control of gonadotropin‐releasing hormone: pulsatile and surge modes of secretion

RL Goodman, AE Herbison… - Journal of …, 2022 - Wiley Online Library
The concept that different systems control episodic and surge secretion of gonadotropin‐
releasing hormone (GnRH) was well established by the time that GnRH was identified and …

The gonadotropin-releasing hormone pulse generator

AE Herbison - Endocrinology, 2018 - academic.oup.com
The pulsatile release of GnRH and LH secretion is essential for fertility in all mammals.
Pulses of LH occur approximately every hour in follicular-phase females and every 2 to 3 …

Hypothalamic tanycytes: a key component of brain–endocrine interaction

EM Rodríguez, JL Blázquez, FE Pastor… - International review of …, 2005 - Elsevier
Tanycytes are bipolar cells bridging the cerebrospinal fluid (CSF) to the portal capillaries
and may link the CSF to neuroendocrine events. During the perinatal period a …

[图书][B] Oxford companion to emotion and the affective sciences

D Sander, K Scherer - 2014 - books.google.com
Few areas have witnessed the type of growth we have seen in the affective sciences in the
past decades. Across psychology, philosophy, economics, and neuroscience, there has …

Kisspeptin, neurokinin B, and dynorphin act in the arcuate nucleus to control activity of the GnRH pulse generator in ewes

RL Goodman, SM Hileman, CC Nestor, KL Porter… - …, 2013 - academic.oup.com
Recent work has led to the hypothesis that kisspeptin/neurokinin B/dynorphin (KNDy)
neurons in the arcuate nucleus play a key role in GnRH pulse generation, with kisspeptin …

Luteinizing hormone action in human oocyte maturation and quality: signaling pathways, regulation, and clinical impact

A Arroyo, B Kim, J Yeh - Reproductive Sciences, 2020 - Springer
The ovarian follicle luteinizing hormone (LH) signaling molecules that regulate oocyte
meiotic maturation have recently been identified. The LH signal reduces preovulatory follicle …

[HTML][HTML] Physiology of GNRH and gonadotropin secretion

P Marques, K Skorupskaite, KS Rozario… - Endotext …, 2022 - ncbi.nlm.nih.gov
Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …

Selective optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion

SY Han, T McLennan, K Czieselsky… - Proceedings of the …, 2015 - National Acad Sciences
Normal reproductive functioning in mammals depends upon gonadotropin-releasing
hormone (GnRH) neurons generating a pulsatile pattern of gonadotropin secretion. The …

Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown

AC Moreira, AM Silva, MS Santos, VA Sardao - The Journal of steroid …, 2014 - Elsevier
Menopause is characterized by an altered hormonal status and by a decrease in life quality
due to the appearance of uncomfortable symptoms. Nowadays, with increasing life span …

Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus

K Maeda, S Ohkura, Y Uenoyama, Y Wakabayashi… - Brain research, 2010 - Elsevier
Gonadotropin-releasing hormone (GnRH) secretion has two modes of release in
mammalian species; the surge mode and the pulse mode. The surge mode, which is …