Microbubble agents: New directions

E Stride, T Segers, G Lajoinie, S Cherkaoui… - Ultrasound in medicine …, 2020 - Elsevier
Microbubble ultrasound contrast agents have now been in use for several decades and their
safety and efficacy in a wide range of diagnostic applications have been well established …

Ultrasound contrast imaging: Fundamentals and emerging technology

H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …

Bursting microbubbles: How nanobubble contrast agents can enable the future of medical ultrasound molecular imaging and image-guided therapy

AA Exner, MC Kolios - Current opinion in colloid & interface science, 2021 - Elsevier
The field of medical ultrasound has undergone a significant evolution since the development
of microbubbles as contrast agents. However, because of their size, microbubbles remain in …

Quantitative frequency-domain passive cavitation imaging

KJ Haworth, KB Bader, KT Rich… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Passive cavitation detection has been an instrumental technique for measuring cavitation
dynamics, elucidating concomitant bioeffects, and guiding ultrasound therapies. Recently …

Recent advances in ultrasound-based diagnosis and therapy with micro-and nanometer-sized formulations

N Güvener, L Appold, F de Lorenzi, SK Golombek… - Methods, 2017 - Elsevier
Ultrasound (US) is one of the most frequently used imaging methods in the clinic. The broad
spectrum of its applications can be increased by the use of gas-filled microbubbles (MB) as …

Passive imaging with pulsed ultrasound insonations

KJ Haworth, TD Mast, K Radhakrishnan… - The Journal of the …, 2012 - pubs.aip.org
Previously, passive cavitation imaging has been described in the context of continuous-
wave high-intensity focused ultrasound thermal ablation. However, the technique has …

[HTML][HTML] Nonlinear dynamics and bifurcation structure of ultrasonically excited lipid coated microbubbles

AJ Sojahrood, H Haghi, R Karshafian… - Ultrasonics Sonochemistry, 2021 - Elsevier
In many applications, microbubbles (MBs) are encapsulated by a lipid coating to increase
their stability. However, the complex behavior of the lipid coating including buckling and …

Characterization of contrast agent microbubbles for ultrasound imaging and therapy research

H Mulvana, RJ Browning, Y Luan… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
The high efficiency with which gas microbubbles can scatter ultrasound compared with the
surrounding blood pool or tissues has led to their widespread employment as contrast …

Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents

JL Raymond, KJ Haworth, KB Bader… - Ultrasound in medicine …, 2014 - Elsevier
The aim of this study was to characterize the frequency-dependent acoustic attenuation of
three phospholipid-shelled ultrasound contrast agents (UCAs): Definity, MicroMarker and …

Ultrasonically triggered drug delivery: breaking the barrier

GA Husseini, WG Pitt, AM Martins - Colloids and surfaces B: Biointerfaces, 2014 - Elsevier
The adverse side-effects of chemotherapy can be minimized by delivering the therapeutics
in time and space to only the desired target site. Ultrasound offers one fairly non-invasive …