Transcriptional regulation of hepatic stellate cells

J Mann, DA Mann - Advanced drug delivery reviews, 2009 - Elsevier
Hepatic stellate cell (HSC) activation is a process of cellular transdifferentiation in which,
upon liver injury, the quiescent vitamin A storing perisinusoidal HSC is converted into a …

Macrophage migration and invasion is regulated by MMP10 expression

MY Murray, TP Birkland, JD Howe, AD Rowan… - PloS one, 2013 - journals.plos.org
This study was designed to identify metalloproteinase determinants of macrophage
migration and led to the specific hypothesis that matrix metalloproteinase 10 …

Transcriptional regulation of stellate cell activation

SL Friedman - Journal of gastroenterology and hepatology, 2006 - Wiley Online Library
The identification of activated hepatic stellate cells and related cell types as key fibrogenic
effectors during liver injury has led to intense evaluation of transcriptional events underlying …

Collagen I induces discoidin domain receptor (DDR) 1 expression through DDR2 and a JAK2-ERK1/2-mediated mechanism in primary human lung fibroblasts

PA Ruiz, G Jarai - Journal of Biological Chemistry, 2011 - ASBMB
Discoidin domain receptors (DDRs) DDR1 and DDR2 are receptor tyrosine kinases with the
unique ability among receptor tyrosine kinases to respond to collagen. Several signaling …

RETRACTED ARTICLE: Knockdown of zinc finger protein 267 suppresses diffuse large B-cell lymphoma progression, metastasis, and cancer stem cell properties

H Yang, L Wang, Y Zheng, G Hu, H Ma, L Shen - Bioengineered, 2022 - Taylor & Francis
Statement of Retraction Hua Yang, Linmei Wang, Yingbin Zheng, Guiming Hu, Hongyan Ma
& Liyun Shen (2022) Knockdown of zinc finger protein 267 suppresses diffuse large B-cell …

Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells

F Tacke, E Gäbele, F Bataille, RF Schwabe… - Digestive diseases and …, 2007 - Springer
Hepatic stellate cells (HSCs) are the main extracellular matrix (ECM)-producing cells in liver
fibrogenesis. The excessive synthesis of ECM proteins deteriorates hepatic architecture and …

Mutations in the C-terminus of the X protein of hepatitis B virus regulate Wnt-5a expression in hepatoma Huh7 cells: cDNA microarray and proteomic analyses

X Liu, L Wang, S Zhang, J Lin, S Zhang… - …, 2008 - academic.oup.com
Background: The hepatitis B virus x gene (HBx) is a promiscuous transactivator implicated in
the development of hepatocellular carcinoma (HCC). The present study was designed to …

Zinc finger protein 267 is up-regulated in hepatocellular carcinoma and promotes tumor cell proliferation and migration

B Schnabl, D Valletta, G Kirovski… - … and molecular pathology, 2011 - Elsevier
Zinc finger protein 267 (ZNF267) belongs to the family of Kruppel-like transcription factors,
which regulates diverse biological processes that include development, proliferation, and …

[HTML][HTML] AI algorithm combined with RNA editing-based blood biomarkers to discriminate bipolar from major depressive disorders in an external validation multicentric …

N Salvetat, FJ Checa-Robles, A Delacrétaz… - Journal of Affective …, 2024 - Elsevier
Bipolar disorder (BD) is a leading cause of disability worldwide, as it can lead to cognitive
and functional impairment and premature mortality. The first episode of BD is usually a …

A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells

B Schnabl, K Brandl, M Fink, P Gross, K Taura… - Biochemical and …, 2008 - Elsevier
Activated hepatic stellate cells (HSCs) play a key role in hepatic fibrogenesis. In injured liver
they are the main extracellular matrix protein producing cell type and further perpetuate …