While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

Significance: Antioxidant and redox signaling (ARS) events are regulated by critical
molecules that modulate antioxidants, reactive oxygen species (ROS) or reactive nitrogen …

Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

The underlying therapeutic mechanism of renal tubular epithelium repair of diabetic
nephropathy (DN) by bone marrow-derived mesenchymal stem cells (BM-MSCs) has not …

Alzheimer's disease (AD) is the leading cause of dementia in the elderly and is
characterized by progressive cognitive and memory deficits. The pathological hallmarks of …

Background Mitochondria, the power plants of the cell, are known as a cross-road of
different cellular signaling pathways. These cytoplasmic double-membraned organelles play …

Resveratrol is a natural compound that mimics the antioxidant and antiaging effects of
caloric restriction, mainly mediated through SIRT1, a deacetylase that induces longevity and …

Eye diseases are currently a major public health concern due to the growing number of
cases resulting from both an aging of populations and exogenous factors linked to our …

Neurodegenerative disorders include different neurological conditions that affect nerve cells,
causing the progressive loss of their functions and ultimately leading to loss of mobility …

Loss of idiopathic retinal ganglion cells (RGCs) leads to irreversible vision defects and is
considered the primary characteristic of glaucoma. However, effective treatment strategies in …